A0A1Y1LMI9 · A0A1Y1LMI9_PHOPY

Function

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentearly endosome membrane
Cellular Componentendoplasmic reticulum membrane
Cellular Componentextracellular region
Cellular ComponentGolgi membrane
Cellular Componentmultivesicular body membrane
Cellular Componentplasma membrane
Cellular Componentrecycling endosome membrane
Cellular Componenttransport vesicle membrane
Biological Processendocytosis
Biological Processpost-Golgi vesicle-mediated transport
Biological Processvacuolar transport

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Sortilin-related receptor
  • Alternative names
    • Low-density lipoprotein receptor relative with 11 ligand-binding repeats
    • Sorting protein-related receptor containing LDLR class A repeats

Organism names

Accessions

  • Primary accession
    A0A1Y1LMI9

Subcellular Location

Cell membrane
; Single-pass membrane protein
Cytoplasmic vesicle, secretory vesicle membrane
; Single-pass type I membrane protein
Early endosome membrane
; Single-pass type I membrane protein
Endoplasmic reticulum membrane
; Single-pass type I membrane protein
Endosome, multivesicular body membrane
; Single-pass type I membrane protein
Golgi apparatus, trans-Golgi network membrane
; Single-pass type I membrane protein
Recycling endosome membrane
; Single-pass type I membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane2062-2085Helical

Keywords

PTM/Processing

Features

Showing features for signal, chain, disulfide bond.

TypeIDPosition(s)Description
Signal1-25
ChainPRO_501311865126-2136
Disulfide bond1069↔1081
Disulfide bond1076↔1094
Disulfide bond1088↔1103
Disulfide bond1108↔1120
Disulfide bond1115↔1133
Disulfide bond1127↔1142
Disulfide bond1147↔1159
Disulfide bond1154↔1172
Disulfide bond1166↔1181
Disulfide bond1210↔1225
Disulfide bond1251↔1266
Disulfide bond1288↔1300
Disulfide bond1295↔1313
Disulfide bond1307↔1322
Disulfide bond1344↔1356
Disulfide bond1351↔1369
Disulfide bond1363↔1378
Disulfide bond1404↔1419
Disulfide bond1434↔1446
Disulfide bond1441↔1459
Disulfide bond1453↔1468

Keywords

Family & Domains

Features

Showing features for repeat, domain, region.

TypeIDPosition(s)Description
Repeat877-922LDL-receptor class B
Repeat923-967LDL-receptor class B
Domain1574-1665Fibronectin type-III
Domain1670-1757Fibronectin type-III
Domain1760-1855Fibronectin type-III
Domain1955-2053Fibronectin type-III
Region2108-2136Disordered

Sequence similarities

Belongs to the VPS10-related sortilin family. SORL1 subfamily.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    2,136
  • Mass (Da)
    240,087
  • Last updated
    2017-08-30 v1
  • Checksum
    D2D89514A0DC0997
MCKMAQSFTLLIYVLLNLCLVNTNGLYGIKEPRHHERKTLVINADSDSDLYNHRHKRDVKGAPVINDNTNVTIITKITHLNDSHKQLMVDWVGEGSNVIICLARDPTPQTSLNPSCVYISYDYGDTYENKTHLFKLENGNFSTVEKFYNHPKYNSHFVFTDVNNKAIFVTKNHGKNITRINVSFTPNEVSFHELRPDTFLVLQKSEPKPQLWITEDFGGSWRLLEEYVNSYFWLQDDKTGEQILVIQRGEVNGLNEIIYSRNLFKSEQLHILASHVKDISFKGDYIFFTKKSSKDNYDLFVSYKLGEQLKCIFDSELDRRGYQVVDVTGSRALVAVSHTDTLSHLYVSENLGGNDDKVHFTLSLEAVLAYFPNSSWHDSWLHHVSEEAFTDVYKVQGITGIYIASQVSGKLVDHNLGPQHLTSLITFDHGGSWRPLNPPVHDNERQLISCSLANNCSLHLSQRFSQLYPETRSISILSSGSAPGVIIATGVIGKSLKGHFGVYISTDAGFTWRQVLKDLFFFNMGDHGGVITAVKYYKNLAETRHILYSTDLGEKWSQVAFHDEDLRLYGLMTEPGENTTVFTMFGSKPHSHQWIIIKLDMRSVFSYNCSKDDYKEWSPSQNDGSRNYVPCVLGKQVTYERRIPHANCYVGLNYVRQISYQPCDCDALDFECDFGFMRSGKPFHCIRNKTTVENPYEVPSTCKPFQFYNRTKGYRKISGDSCVAGFEHQYLPDLIPCPFKEVRQFLLFALRDRIGRYDLLNHKLEHLPIQNLKNVIAIDFDMKNNCVYWADIVTDTIGRQCFGNGSTPEILVSHDLASIEGMAFDWISQHLYFVDGMRAKIELIRTDINHSGRMRKTILDSRNLRKPRGIAVHPRAGYLFWTDWASETSSVSRSNLDGTKVRTLFDKKVVEWPNGITIDYIAERIYWVDAREDYIASSDLNGERFKKIIKDNDLVSHPFAVAVFKDNMYWDDWKQNSVFSADKDSGVAIELLLKQLQGLMDLKVFAHSLQEGTNGCSNSTCSHICVSAPKQGHVCLCPDGMDMKGTTCVCPGGVEPYSNKTCPKIASTCGGEHFACSNGVCVPKGWRCDGEDDCGDASDELLCGPQTCAHNYFVCGDGKCLPQYWRCDYERDCTDGSDELNCPKQNCSATQFACGNGRCISARWKCDGENDCRDGSDEKDCVGPDPTTCKSDEFHCTGGGVSCIPTTWRCDLENDCKDGSDELNCSNNTCAEYQFACGAPTYRCIYASWVCDGEQDCPDGIDEKNCTAIDKPPMATPNPFLPTNGTSCLDWMFMCSNRKCIPYWWKCDSADDCGDNSDEIGCLNVAKTTLAPVPTTPHPIYRTCSHNEYQCTSGECIELSWVCDGSRDCPQGEEEENCDGIRHCSGDEFKCRMDGTCVPLTDVCNGHKDCPDGTDESACSTDHNVPSGSAGPSCSVGYFPCDDFMCHPLAMLCDNKIDCRDGFDEKNCSSVTRVYQVLQMGVDERSINETSLLLYWWIPLPDKVKLEFLPSISKQGSNKFDNKTWTEHTEYRFMNLEPFTKYNMTVYVKLKDSSNVFPPAKYFIANTGEGVPSEPWNVTVEQQNGSHTLISWKKPITPNGIIQYYEICWFPPEPPIKLKLSDDSTAHLLPADFPPDHKYSFYVIAHNRAHESNHSDIKSIIFDGDSDLNAVINLSVVSKTTNSISLSWQYERAVDGFTVKIEALHPYPQLPSRTTTAKNIVMDNLAPGVYYTFKVKAFRKSFQGIPSSIAARTSGDPLPVIHKLEALVDKSVGTSVKLTWERPKDSRKVAWVYGVYYGLNEEETLQKSRLNTTDTTVTVTHLGACETYIFSVGIVGPSGVGNISSDSPTVMTSLNKRAAPKRLTVTQHPSDHLKMQVSWSASCPTFAEPVGYIITILDKLTNEVVNHNKLESKDIELSSTFRVTYGGVYDIKVSTSIVGAIYTHPVTYYAPPIPPPRGLRVFLERNGSYILNWQEREIPSEIGSHKYEIFVSKGDMLNTSSASKFVVLKPPFLFENDDAPSMYTFGVQIVSERGYRSLLSEWPAANYAQTQSSLELIGKSNMTAILVPACILLVALGGALAFLIIRNRRLQNSFTRFANSHYDTRSGAATFDDNGLEEDESPQIRGFSDDEPLVIA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
GEZM01051492
EMBL· GenBank· DDBJ
JAV74849.1
EMBL· GenBank· DDBJ
Transcribed RNA

Similar Proteins

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