A0A1Y1LMI9 · A0A1Y1LMI9_PHOPY
- ProteinSortilin-related receptor
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids2136 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | early endosome membrane | |
Cellular Component | endoplasmic reticulum membrane | |
Cellular Component | extracellular region | |
Cellular Component | Golgi membrane | |
Cellular Component | multivesicular body membrane | |
Cellular Component | plasma membrane | |
Cellular Component | recycling endosome membrane | |
Cellular Component | transport vesicle membrane | |
Biological Process | endocytosis | |
Biological Process | post-Golgi vesicle-mediated transport | |
Biological Process | vacuolar transport |
Keywords
- Molecular function
- Biological process
Names & Taxonomy
Protein names
- Recommended nameSortilin-related receptor
- Alternative names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Coleoptera > Polyphaga > Elateriformia > Elateroidea > Lampyridae > Lampyrinae > Photinus
Accessions
- Primary accessionA0A1Y1LMI9
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Single-pass membrane protein
Cytoplasmic vesicle, secretory vesicle membrane ; Single-pass type I membrane protein
Early endosome membrane ; Single-pass type I membrane protein
Endoplasmic reticulum membrane ; Single-pass type I membrane protein
Endosome, multivesicular body membrane ; Single-pass type I membrane protein
Golgi apparatus, trans-Golgi network membrane ; Single-pass type I membrane protein
Recycling endosome membrane ; Single-pass type I membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 2062-2085 | Helical | ||||
Sequence: MTAILVPACILLVALGGALAFLII |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for signal, chain, disulfide bond.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-25 | |||||
Sequence: MCKMAQSFTLLIYVLLNLCLVNTNG | ||||||
Chain | PRO_5013118651 | 26-2136 | Sortilin-related receptor | |||
Sequence: LYGIKEPRHHERKTLVINADSDSDLYNHRHKRDVKGAPVINDNTNVTIITKITHLNDSHKQLMVDWVGEGSNVIICLARDPTPQTSLNPSCVYISYDYGDTYENKTHLFKLENGNFSTVEKFYNHPKYNSHFVFTDVNNKAIFVTKNHGKNITRINVSFTPNEVSFHELRPDTFLVLQKSEPKPQLWITEDFGGSWRLLEEYVNSYFWLQDDKTGEQILVIQRGEVNGLNEIIYSRNLFKSEQLHILASHVKDISFKGDYIFFTKKSSKDNYDLFVSYKLGEQLKCIFDSELDRRGYQVVDVTGSRALVAVSHTDTLSHLYVSENLGGNDDKVHFTLSLEAVLAYFPNSSWHDSWLHHVSEEAFTDVYKVQGITGIYIASQVSGKLVDHNLGPQHLTSLITFDHGGSWRPLNPPVHDNERQLISCSLANNCSLHLSQRFSQLYPETRSISILSSGSAPGVIIATGVIGKSLKGHFGVYISTDAGFTWRQVLKDLFFFNMGDHGGVITAVKYYKNLAETRHILYSTDLGEKWSQVAFHDEDLRLYGLMTEPGENTTVFTMFGSKPHSHQWIIIKLDMRSVFSYNCSKDDYKEWSPSQNDGSRNYVPCVLGKQVTYERRIPHANCYVGLNYVRQISYQPCDCDALDFECDFGFMRSGKPFHCIRNKTTVENPYEVPSTCKPFQFYNRTKGYRKISGDSCVAGFEHQYLPDLIPCPFKEVRQFLLFALRDRIGRYDLLNHKLEHLPIQNLKNVIAIDFDMKNNCVYWADIVTDTIGRQCFGNGSTPEILVSHDLASIEGMAFDWISQHLYFVDGMRAKIELIRTDINHSGRMRKTILDSRNLRKPRGIAVHPRAGYLFWTDWASETSSVSRSNLDGTKVRTLFDKKVVEWPNGITIDYIAERIYWVDAREDYIASSDLNGERFKKIIKDNDLVSHPFAVAVFKDNMYWDDWKQNSVFSADKDSGVAIELLLKQLQGLMDLKVFAHSLQEGTNGCSNSTCSHICVSAPKQGHVCLCPDGMDMKGTTCVCPGGVEPYSNKTCPKIASTCGGEHFACSNGVCVPKGWRCDGEDDCGDASDELLCGPQTCAHNYFVCGDGKCLPQYWRCDYERDCTDGSDELNCPKQNCSATQFACGNGRCISARWKCDGENDCRDGSDEKDCVGPDPTTCKSDEFHCTGGGVSCIPTTWRCDLENDCKDGSDELNCSNNTCAEYQFACGAPTYRCIYASWVCDGEQDCPDGIDEKNCTAIDKPPMATPNPFLPTNGTSCLDWMFMCSNRKCIPYWWKCDSADDCGDNSDEIGCLNVAKTTLAPVPTTPHPIYRTCSHNEYQCTSGECIELSWVCDGSRDCPQGEEEENCDGIRHCSGDEFKCRMDGTCVPLTDVCNGHKDCPDGTDESACSTDHNVPSGSAGPSCSVGYFPCDDFMCHPLAMLCDNKIDCRDGFDEKNCSSVTRVYQVLQMGVDERSINETSLLLYWWIPLPDKVKLEFLPSISKQGSNKFDNKTWTEHTEYRFMNLEPFTKYNMTVYVKLKDSSNVFPPAKYFIANTGEGVPSEPWNVTVEQQNGSHTLISWKKPITPNGIIQYYEICWFPPEPPIKLKLSDDSTAHLLPADFPPDHKYSFYVIAHNRAHESNHSDIKSIIFDGDSDLNAVINLSVVSKTTNSISLSWQYERAVDGFTVKIEALHPYPQLPSRTTTAKNIVMDNLAPGVYYTFKVKAFRKSFQGIPSSIAARTSGDPLPVIHKLEALVDKSVGTSVKLTWERPKDSRKVAWVYGVYYGLNEEETLQKSRLNTTDTTVTVTHLGACETYIFSVGIVGPSGVGNISSDSPTVMTSLNKRAAPKRLTVTQHPSDHLKMQVSWSASCPTFAEPVGYIITILDKLTNEVVNHNKLESKDIELSSTFRVTYGGVYDIKVSTSIVGAIYTHPVTYYAPPIPPPRGLRVFLERNGSYILNWQEREIPSEIGSHKYEIFVSKGDMLNTSSASKFVVLKPPFLFENDDAPSMYTFGVQIVSERGYRSLLSEWPAANYAQTQSSLELIGKSNMTAILVPACILLVALGGALAFLIIRNRRLQNSFTRFANSHYDTRSGAATFDDNGLEEDESPQIRGFSDDEPLVIA | ||||||
Disulfide bond | 1069↔1081 | |||||
Sequence: CGGEHFACSNGVC | ||||||
Disulfide bond | 1076↔1094 | |||||
Sequence: CSNGVCVPKGWRCDGEDDC | ||||||
Disulfide bond | 1088↔1103 | |||||
Sequence: CDGEDDCGDASDELLC | ||||||
Disulfide bond | 1108↔1120 | |||||
Sequence: CAHNYFVCGDGKC | ||||||
Disulfide bond | 1115↔1133 | |||||
Sequence: CGDGKCLPQYWRCDYERDC | ||||||
Disulfide bond | 1127↔1142 | |||||
Sequence: CDYERDCTDGSDELNC | ||||||
Disulfide bond | 1147↔1159 | |||||
Sequence: CSATQFACGNGRC | ||||||
Disulfide bond | 1154↔1172 | |||||
Sequence: CGNGRCISARWKCDGENDC | ||||||
Disulfide bond | 1166↔1181 | |||||
Sequence: CDGENDCRDGSDEKDC | ||||||
Disulfide bond | 1210↔1225 | |||||
Sequence: CDLENDCKDGSDELNC | ||||||
Disulfide bond | 1251↔1266 | |||||
Sequence: CDGEQDCPDGIDEKNC | ||||||
Disulfide bond | 1288↔1300 | |||||
Sequence: CLDWMFMCSNRKC | ||||||
Disulfide bond | 1295↔1313 | |||||
Sequence: CSNRKCIPYWWKCDSADDC | ||||||
Disulfide bond | 1307↔1322 | |||||
Sequence: CDSADDCGDNSDEIGC | ||||||
Disulfide bond | 1344↔1356 | |||||
Sequence: CSHNEYQCTSGEC | ||||||
Disulfide bond | 1351↔1369 | |||||
Sequence: CTSGECIELSWVCDGSRDC | ||||||
Disulfide bond | 1363↔1378 | |||||
Sequence: CDGSRDCPQGEEEENC | ||||||
Disulfide bond | 1404↔1419 | |||||
Sequence: CNGHKDCPDGTDESAC | ||||||
Disulfide bond | 1434↔1446 | |||||
Sequence: CSVGYFPCDDFMC | ||||||
Disulfide bond | 1441↔1459 | |||||
Sequence: CDDFMCHPLAMLCDNKIDC | ||||||
Disulfide bond | 1453↔1468 | |||||
Sequence: CDNKIDCRDGFDEKNC |
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for repeat, domain, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Repeat | 877-922 | LDL-receptor class B | ||||
Sequence: GYLFWTDWASETSSVSRSNLDGTKVRTLFDKKVVEWPNGITIDYIA | ||||||
Repeat | 923-967 | LDL-receptor class B | ||||
Sequence: ERIYWVDAREDYIASSDLNGERFKKIIKDNDLVSHPFAVAVFKDN | ||||||
Domain | 1574-1665 | Fibronectin type-III | ||||
Sequence: EPWNVTVEQQNGSHTLISWKKPITPNGIIQYYEICWFPPEPPIKLKLSDDSTAHLLPADFPPDHKYSFYVIAHNRAHESNHSDIKSIIFDGD | ||||||
Domain | 1670-1757 | Fibronectin type-III | ||||
Sequence: AVINLSVVSKTTNSISLSWQYERAVDGFTVKIEALHPYPQLPSRTTTAKNIVMDNLAPGVYYTFKVKAFRKSFQGIPSSIAARTSGDP | ||||||
Domain | 1760-1855 | Fibronectin type-III | ||||
Sequence: VIHKLEALVDKSVGTSVKLTWERPKDSRKVAWVYGVYYGLNEEETLQKSRLNTTDTTVTVTHLGACETYIFSVGIVGPSGVGNISSDSPTVMTSLN | ||||||
Domain | 1955-2053 | Fibronectin type-III | ||||
Sequence: PPRGLRVFLERNGSYILNWQEREIPSEIGSHKYEIFVSKGDMLNTSSASKFVVLKPPFLFENDDAPSMYTFGVQIVSERGYRSLLSEWPAANYAQTQSS | ||||||
Region | 2108-2136 | Disordered | ||||
Sequence: AATFDDNGLEEDESPQIRGFSDDEPLVIA |
Sequence similarities
Belongs to the VPS10-related sortilin family. SORL1 subfamily.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length2,136
- Mass (Da)240,087
- Last updated2017-08-30 v1
- ChecksumD2D89514A0DC0997