A0A1X9YK79 · A0A1X9YK79_9SPHN

  • Protein
    Glycerol kinase
  • Gene
    glpK
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Activity regulation

Inhibited by fructose 1,6-bisphosphate (FBP).

Pathway

Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site14ADP (UniProtKB | ChEBI)
Binding site14ATP (UniProtKB | ChEBI)
Binding site14sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site15ATP (UniProtKB | ChEBI)
Binding site16ATP (UniProtKB | ChEBI)
Binding site18ADP (UniProtKB | ChEBI)
Binding site84glycerol (UniProtKB | ChEBI)
Binding site84sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site85glycerol (UniProtKB | ChEBI)
Binding site85sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site136glycerol (UniProtKB | ChEBI)
Binding site136sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site245glycerol (UniProtKB | ChEBI)
Binding site245sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site246glycerol (UniProtKB | ChEBI)
Binding site267ADP (UniProtKB | ChEBI)
Binding site267ATP (UniProtKB | ChEBI)
Binding site310ADP (UniProtKB | ChEBI)
Binding site310ATP (UniProtKB | ChEBI)
Binding site411ADP (UniProtKB | ChEBI)
Binding site411ATP (UniProtKB | ChEBI)
Binding site415ADP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular FunctionATP binding
Molecular Functionglycerol kinase activity
Biological Processglycerol catabolic process
Biological Processglycerol-3-phosphate metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glycerol kinase
  • EC number
  • Alternative names
    • ATP:glycerol 3-phosphotransferase
    • Glycerokinase
      (GK
      )

Gene names

    • Name
      glpK
    • ORF names
      KC8_17815

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • KC8
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Alphaproteobacteria > Sphingomonadales > Sphingomonadaceae > Sphingomonas

Accessions

  • Primary accession
    A0A1X9YK79

Proteomes

Subcellular Location

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain7-252Carbohydrate kinase FGGY N-terminal
Domain262-450Carbohydrate kinase FGGY C-terminal

Sequence similarities

Belongs to the FGGY kinase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    495
  • Mass (Da)
    52,703
  • Last updated
    2017-08-30 v1
  • Checksum
    A302EDF8831F2AA5
MPEPHNILAIDQGTTSTRSIIFDAQARVLATAQAEFAQHYPQDGWVEHDAEDIWRDTLATAREAIAKAALNASDIAAIGITNQRETTVLWDRATGTPLHKAIVWQDRRTADHCAALKAAGHEALVRARTGLLIDPYFSATKLGWLLDHVPGARARAERGELAFGTIDSFLLWRMTGGRVHATDATNASRTMLFDIHRQIWCEELLDLFGIPTSLLPEVRDSSGLFGLCDPDLFGAAIPIAGIAGDQQAALVGQACFGAGMAKATYGTGCFMLLNTGEQAVASDKRLLTTTAYRLEGKVAYAVEGSIFVAGAAIKWLRDGLGLITHASQTDDLATRVADNGGVYMVPAFVGLGAPHWDAHARGLICGLTLNSSAAHVARAALESIGYQTADLVTAMMEDGAAQPSALRVDGGMSANDWLCQFLADILEIPVERPANLETTALGAAFLAGMGVGLWDGPVGVAALTRRADRFEPAGDQENRAALLAGWRKALERALA

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP016306
EMBL· GenBank· DDBJ
ARS29131.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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