A0A1X9YAA4 · A0A1X9YAA4_9SPHN

  • Protein
    Anthranilate phosphoribosyltransferase
  • Gene
    trpD
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 2 magnesium ions per monomer.

Pathway

Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 2/5.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site785-phospho-alpha-D-ribose 1-diphosphate (UniProtKB | ChEBI)
Binding site78anthranilate 1 (UniProtKB | ChEBI)
Binding site81-825-phospho-alpha-D-ribose 1-diphosphate (UniProtKB | ChEBI)
Binding site865-phospho-alpha-D-ribose 1-diphosphate (UniProtKB | ChEBI)
Binding site88-915-phospho-alpha-D-ribose 1-diphosphate (UniProtKB | ChEBI)
Binding site90Mg2+ 1 (UniProtKB | ChEBI)
Binding site106-1145-phospho-alpha-D-ribose 1-diphosphate (UniProtKB | ChEBI)
Binding site109anthranilate 1 (UniProtKB | ChEBI)
Binding site1185-phospho-alpha-D-ribose 1-diphosphate (UniProtKB | ChEBI)
Binding site164anthranilate 2 (UniProtKB | ChEBI)
Binding site223Mg2+ 2 (UniProtKB | ChEBI)
Binding site224Mg2+ 2 (UniProtKB | ChEBI)
Binding site224Mg2+ 1 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionanthranilate phosphoribosyltransferase activity
Molecular Functionmagnesium ion binding
Biological Processtryptophan biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Anthranilate phosphoribosyltransferase
  • EC number

Gene names

    • Name
      trpD
    • ORF names
      KC8_00345

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • KC8
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Alphaproteobacteria > Sphingomonadales > Sphingomonadaceae > Sphingomonas

Accessions

  • Primary accession
    A0A1X9YAA4

Proteomes

Subcellular Location

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain13-63Glycosyl transferase family 3 N-terminal
Domain73-321Glycosyl transferase family 3

Sequence similarities

Belongs to the anthranilate phosphoribosyltransferase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    331
  • Mass (Da)
    34,234
  • Last updated
    2017-08-30 v1
  • Checksum
    DA2515DE118E3172
MTITTVLPDAHLPLDQATAHAAFADMLDGRANEAEAQAFLTVMAERDETSVEIAAAAMALRERMIPITAPAGAIDVCGTGGDGAHSLNVSTAVAIVVAACGVPVAKHGNRAASSKAGSSDTLEALGLDLDRASARAEASLNDLGIAFLFAQLHHPSLKRLAAVRRAIGRRTIFNLIGPIANPARVTRQLIGVARPDYLPVYADALRLIGTESAMMVAGDEPLDELSIAGPSSAIRIGACGEGAIRIVPEDAGLTRHPLEALRGGDAVYNADALRRLLLGEQGAYRDAVLLNAAAALIVAGHATDLHAGVEEAAETIDKGLAKALLDCWIAF

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP016306
EMBL· GenBank· DDBJ
ARS25743.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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