A0A1X3D4T3 · A0A1X3D4T3_9NEIS

  • Protein
    Exodeoxyribonuclease III
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Note: Probably binds two magnesium or manganese ions per subunit.

Features

Showing features for binding site, active site, site.

125620406080100120140160180200220240
Type
IDPosition(s)Description
Binding site7Mg2+ 1 (UniProtKB | ChEBI)
Binding site34Mg2+ 1 (UniProtKB | ChEBI)
Active site105
Active site146Proton donor/acceptor
Binding site146Mg2+ 1 (UniProtKB | ChEBI)
Binding site148Mg2+ 1 (UniProtKB | ChEBI)
Site148Transition state stabilizer
Site217Important for catalytic activity
Binding site246Mg2+ 1 (UniProtKB | ChEBI)
Active site247Proton acceptor
Binding site247Mg2+ 1 (UniProtKB | ChEBI)
Site247Interaction with DNA substrate

GO annotations

AspectTerm
Molecular FunctionDNA binding
Molecular Functiondouble-stranded DNA 3'-5' DNA exonuclease activity
Molecular Functionendonuclease activity
Molecular Functionmetal ion binding
Biological ProcessDNA repair

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Exodeoxyribonuclease III

Gene names

    • ORF names
      BV912_12380

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • 124861
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Betaproteobacteria > Neisseriales > Neisseriaceae > Neisseria

Accessions

  • Primary accession
    A0A1X3D4T3

Proteomes

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain4-247Endonuclease/exonuclease/phosphatase

Sequence similarities

Belongs to the DNA repair enzymes AP/ExoA family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    256
  • Mass (Da)
    29,647
  • Last updated
    2017-07-05 v1
  • Checksum
    526CC2FE76E6145A
MKIATWNVNSLNVRLPQVQDWLQQHSPDILVLQELKLDQDKYPAAVFQMSGWHTVWSGQKTYNGVAIISKTEPQDIHTGLPALPEDPQRRVIAATIGGVRVINVYCVNGEAPDSPKFQYKEQWFAALTEFVRDEMSRHEKLVLLGDFNIAPADLDCYDPEKWHEKIHCTGIERSWFQNLLDLGLTDSLRHRYPQEVMYTWWDYRGAMFQRKQGLRIDHLLVTPALRDALQDVQVDLEARAQERPSDHAPVWATFDI

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MTAB01000055
EMBL· GenBank· DDBJ
OSI14755.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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