A0A1X2H7V2 · A0A1X2H7V2_SYNRA
- ProteinATP-binding cassette sub-family B member 6
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1014 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
Catalytic activity
- ATP + H2O + heme b(in) = ADP + H+ + heme b(out) + phosphateThis reaction proceeds in the forward direction.
CHEBI:30616 + CHEBI:15377 + heme b (in)CHEBI:60344= CHEBI:456216 + CHEBI:15378 + heme b (out)CHEBI:60344+ CHEBI:43474 - ATP + H2O + pheophorbide a(in) = ADP + H+ + pheophorbide a(out) + phosphateThis reaction proceeds in the forward direction.
- ATP + H2O + protoporphyrin IX(in) = ADP + H+ + phosphate + protoporphyrin IX(out)This reaction proceeds in the forward direction.
- ATP + H2O + uroporphyrin I(in) = ADP + H+ + phosphate + uroporphyrin I(out)This reaction proceeds in the forward direction.
- ATP + H2O + uroporphyrin III(in) = ADP + H+ + phosphate + uroporphyrin III(out)This reaction proceeds in the forward direction.
- ATP + coproporphyrin I(in) + H2O = ADP + coproporphyrin I(out) + H+ + phosphateThis reaction proceeds in the forward direction.
- ATP + coproporphyrin III(in) + H2O = ADP + coproporphyrin III(out) + H+ + phosphateThis reaction proceeds in the forward direction.
- ATP + coproporphyrinogen III(in) + H2O = ADP + coproporphyrinogen III(out) + H+ + phosphateThis reaction proceeds in the forward direction.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | early endosome membrane | |
Cellular Component | extracellular region | |
Cellular Component | Golgi membrane | |
Cellular Component | mitochondrial outer membrane | |
Cellular Component | multivesicular body membrane | |
Cellular Component | vacuolar membrane | |
Molecular Function | ABC-type transporter activity | |
Molecular Function | ATP binding | |
Molecular Function | ATP hydrolysis activity |
Keywords
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameATP-binding cassette sub-family B member 6
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Fungi incertae sedis > Mucoromycota > Mucoromycotina > Mucoromycetes > Mucorales > Syncephalastraceae > Syncephalastrum
Accessions
- Primary accessionA0A1X2H7V2
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Golgi apparatus membrane ; Multi-pass membrane protein
Membrane ; Multi-pass membrane protein
Mitochondrion outer membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 30-54 | Helical | ||||
Sequence: WATPFFTTPTALLVVVVVFGLGRYL | ||||||
Transmembrane | 75-99 | Helical | ||||
Sequence: LSKLIVALAITIVVTFLGDAGVVVA | ||||||
Transmembrane | 111-130 | Helical | ||||
Sequence: VFAYYIGVSWLAWVLSLVSL | ||||||
Transmembrane | 142-163 | Helical | ||||
Sequence: WVQYIFWMAAFLGETMVGWLWA | ||||||
Transmembrane | 183-205 | Helical | ||||
Sequence: LGIFVTRYILELGTVLLCVINMF | ||||||
Transmembrane | 263-284 | Helical | ||||
Sequence: VWLQLLVLACFCLMLVGLAVNA | ||||||
Transmembrane | 304-325 | Helical | ||||
Sequence: FAWAAVLAYVGLRFLQGGSGLI | ||||||
Transmembrane | 382-406 | Helical | ||||
Sequence: LLSQILFQVLPALANILVAVFVFTF | ||||||
Transmembrane | 412-431 | Helical | ||||
Sequence: FGLIVFVTMALYLFVTISLT | ||||||
Transmembrane | 498-517 | Helical | ||||
Sequence: LMQNAVITAGLLAGCLLFAW |
Keywords
- Cellular component
PTM/Processing
Keywords
- PTM
Interaction
Structure
Family & Domains
Features
Showing features for domain, compositional bias, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 270-555 | ABC transmembrane type-1 | ||||
Sequence: LACFCLMLVGLAVNALTPLQIGYVVDSFGDGKGRFAWAAVLAYVGLRFLQGGSGLIQSLQNWLWIPIGQYTTREISVKMFSHLHGLSLQFHINRKTGEVLRVMDRGTNSIVQLLSQILFQVLPALANILVAVFVFTFKFSPPFGLIVFVTMALYLFVTISLTEWRTKYRRKMIELDNSARTKAVDSLLNFETVKYYGAEDFEIGRYQDAIREYQKADWKSSTSLNVLNLMQNAVITAGLLAGCLLFAWEVSEGRLTAGNFVTYNMYMMQLYTPLHFFGTYYRMIQQ | ||||||
Domain | 589-823 | ABC transporter | ||||
Sequence: VVFDNVSFAYDPRQNALNGISFSIPRGATVALVGPSGGGKSTILRLLFRFYDPSSGHIYIDGQDISQIRQQSLRQNIGVVPQDTVLFNDTIMYNIGYGNVHAPEDAIFKAAKAAQIHDKILQFPDGYDTKVGERGLRLSGGEKQRVAIARTILKDPPIILLDEATSALDTGTERQIQQALSAMTHDRTTLIIAHRLSTIVNADLILVIKDGQVVESGSHDELMRQAVANGNEGIY | ||||||
Compositional bias | 832-855 | Basic and acidic residues | ||||
Sequence: HDDDDGTTQNDSEENSKDDKMDEV | ||||||
Region | 832-1014 | Disordered | ||||
Sequence: HDDDDGTTQNDSEENSKDDKMDEVSAPASAVPREEVQAQKKLTSSGIENTKKQEASPYQERSITDNTKKEEPIATAAEVEDAEARKAEENLSRAEEALTPATNSAPEQPAEPPSVTRIDTQPPMTREANLMSSPTEVAPSTQDDSSNQPATSGTPAATTQPSSAKSPPKNRKKKKKSKSRTTF | ||||||
Compositional bias | 869-893 | Polar residues | ||||
Sequence: AQKKLTSSGIENTKKQEASPYQERS | ||||||
Compositional bias | 894-924 | Basic and acidic residues | ||||
Sequence: ITDNTKKEEPIATAAEVEDAEARKAEENLSR | ||||||
Compositional bias | 927-997 | Polar residues | ||||
Sequence: EALTPATNSAPEQPAEPPSVTRIDTQPPMTREANLMSSPTEVAPSTQDDSSNQPATSGTPAATTQPSSAKS | ||||||
Compositional bias | 998-1014 | Basic residues | ||||
Sequence: PPKNRKKKKKSKSRTTF |
Sequence similarities
Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,014
- Mass (Da)113,096
- Last updated2017-07-05 v1
- Checksum8CE4D0EABD97D6E5
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 832-855 | Basic and acidic residues | ||||
Sequence: HDDDDGTTQNDSEENSKDDKMDEV | ||||||
Compositional bias | 869-893 | Polar residues | ||||
Sequence: AQKKLTSSGIENTKKQEASPYQERS | ||||||
Compositional bias | 894-924 | Basic and acidic residues | ||||
Sequence: ITDNTKKEEPIATAAEVEDAEARKAEENLSR | ||||||
Compositional bias | 927-997 | Polar residues | ||||
Sequence: EALTPATNSAPEQPAEPPSVTRIDTQPPMTREANLMSSPTEVAPSTQDDSSNQPATSGTPAATTQPSSAKS | ||||||
Compositional bias | 998-1014 | Basic residues | ||||
Sequence: PPKNRKKKKKSKSRTTF |
Keywords
- Technical term