A0A1X2GZI5 · A0A1X2GZI5_SYNRA

Function

function

Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Co2+ (UniProtKB | Rhea| CHEBI:48828 )

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Ca2+ (UniProtKB | Rhea| CHEBI:29108 )

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Co2+ (UniProtKB | Rhea| CHEBI:48828 )

Note: Binds 1 Mg2+ ion per subunit. Can also utilize other divalent metal cations, such as Ca2+, Mn2+ and Co2+.
thiamine diphosphate (UniProtKB | Rhea| CHEBI:58937 )

Note: Binds 1 thiamine pyrophosphate per subunit.

Features

Showing features for site.

TypeIDPosition(s)Description
Site28Important for catalytic activity
Site262Important for catalytic activity

GO annotations

AspectTerm
Cellular Componentcytosol
Cellular Componentnucleus
Molecular Functionmetal ion binding
Molecular Functiontransketolase activity
Biological Processpentose-phosphate shunt

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Transketolase
  • EC number

Gene names

    • ORF names
      BCR43DRAFT_499749

Organism names

Accessions

  • Primary accession
    A0A1X2GZI5

Proteomes

Subcellular Location

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain354-530Transketolase-like pyrimidine-binding

Sequence similarities

Belongs to the transketolase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    677
  • Mass (Da)
    72,736
  • Last updated
    2017-07-05 v1
  • Checksum
    4CE7F6ECEEE4B498
MVQSIEQQAINTVRVLAADVVKGANSGHPGAPMGCAPMAHVLFNQMTFNPKNPKFINRDRFVLSNGHGCALQYIYLHLLGYDVSMDDLKQFRQIGSKTPGHPESADTPGIEVTTGPLGQGISNAVGLAIAQEHLAATFNKPGFELFNNHTYVILGDGCLQEGVAAEAISLAGHLKLGKLIALYDDNSITIDGDTAVSFTEDTVKRFESYGWHVSSVADGDNDIAAIQQAVEQAKAVTDKPSLIKIKTTIGYGSLNQGKEKVHGSPLADDDIKQVKQKLGFNPDEKYVVPNEVYEYYGARAAHGAQAEAAWNALYQKYTEQFPQEAAELSRRLAGKLPENWQQALPRFTPADAAVATRKLSEGVLTALSEIIPDLVGGSADLTGSNLTRWKKAVDFQHPSTGLGDYSGRYVRYGVREHAMFAIMNGLAAYGGIIPFGGTFLNFLTYGWGAARLSALSHLRVIYVMTHDSIGLGEDGPTHQPIETLTISRATPNMLTFRPADGNEVSGTYLVAIENAHRPSVIALSRQNLPQLEGSSIEAVTKGAYILQDAPNAKVAFVATGSEVSLAVEAAKKLADEGVPARVVSMPCSELFDEQPLEYRKSVFPAGLPVVSVEALGTYGWEKYAHAHVGMTTFGASGPAPALYKKFGITADAAAEKAKKVAAYYEKTGYVPELGLQF

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MCGN01000013
EMBL· GenBank· DDBJ
ORY89956.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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