A0A1X2A713 · A0A1X2A713_9MYCO

  • Protein
    Isopentenyl-diphosphate delta-isomerase
  • Gene
    fni
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
FMN (UniProtKB | Rhea| CHEBI:58210 )

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

NADPH (UniProtKB | Rhea| CHEBI:57783 )

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site11-12substrate
Binding site70-72FMN (UniProtKB | ChEBI)
Binding site100FMN (UniProtKB | ChEBI)
Binding site100-102substrate
Binding site131FMN (UniProtKB | ChEBI)
Binding site165substrate
Binding site166Mg2+ (UniProtKB | ChEBI)
Binding site197FMN (UniProtKB | ChEBI)
Binding site231FMN (UniProtKB | ChEBI)
Binding site278-280FMN (UniProtKB | ChEBI)
Binding site299-300FMN (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionFMN binding
Molecular Functionisopentenyl-diphosphate delta-isomerase activity
Molecular Functionmagnesium ion binding
Molecular FunctionNADPH binding
Molecular Functionoxidoreductase activity
Biological Processisoprenoid biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Isopentenyl-diphosphate delta-isomerase
  • EC number
  • Short names
    IPP isomerase
  • Alternative names
    • Isopentenyl diphosphate:dimethylallyl diphosphate isomerase
    • Isopentenyl pyrophosphate isomerase
    • Type 2 isopentenyl diphosphate isomerase
      (IDI-2
      )

Gene names

    • Name
      fni
    • ORF names
      AWB90_17775

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • IEC33
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Mycobacteriales > Mycobacteriaceae > Mycobacterium > Mycobacterium simiae complex

Accessions

  • Primary accession
    A0A1X2A713

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homooctamer. Dimer of tetramers.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain251-340FMN-dependent dehydrogenase

Sequence similarities

Belongs to the IPP isomerase type 2 family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    348
  • Mass (Da)
    36,452
  • Last updated
    2017-07-05 v1
  • Checksum
    9C49F18A83621BE1
MTADRGEMSRRKRRHIDVCLDGEVEYRGLTTGLERYALPYNALTQTNLDDIDLGTEFLGARLRAPVLIGAMTGGAELSGTINRNLAGAAQRLGIGMMLGSQRVMLDSALGERAAASFAVRDVAPGVLLFGNIGLSQLTKDAVPDIIRALDRVGANALAVHTNPLQEAVQHHGDTDFAGSLDRLHDLAGALGYPVLLKEVGHGIGAAAIGELLRWSGEPPVAAIDVAGAGGTSWSRVEQLVRYGELRYPDLADWGIPTAQAIGEVRAALPDIPLVASGGIRTGMDAAKALALGADVVAVARPLLPAAIESAEAATAWLQRFVDELRICLHGCGAADLRALRDVGVTPIS

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LQPN01000059
EMBL· GenBank· DDBJ
ORW43016.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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