A0A1X0XLA1 · A0A1X0XLA1_9BACT

Function

function

Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site45
Active site370Nucleophile

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionL-methionine:thioredoxin-disulfide S-oxidoreductase activity
Molecular Functionpeptide-methionine (R)-S-oxide reductase activity
Molecular Functionpeptide-methionine (S)-S-oxide reductase activity
Biological Processprotein modification process
Biological Processprotein repair
Biological Processresponse to oxidative stress

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Multifunctional fusion protein

Including 2 domains:

  • Recommended name
    Peptide methionine sulfoxide reductase MsrA
  • EC number
  • Short names
    Protein-methionine-S-oxide reductase
  • Alternative names
    • Peptide-methionine (S)-S-oxide reductase
      (Peptide Met(O) reductase
      )
  • Recommended name
    Peptide methionine sulfoxide reductase MsrB
  • EC number
  • Alternative names
    • Peptide-methionine (R)-S-oxide reductase

Gene names

    • Name
      msrA
    • Synonyms
      msrB
    • ORF names
      B5V00_16290

Organism names

  • Taxonomic identifier
  • Strain
    • EPR-M
  • Taxonomic lineage
    Bacteria > Thermodesulfobacteriota > Desulfuromonadia > Desulfuromonadales > Geothermobacteraceae > Geothermobacter

Accessions

  • Primary accession
    A0A1X0XLA1

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for signal, chain.

TypeIDPosition(s)Description
Signal1-21
ChainPRO_501336676322-397Multifunctional fusion protein

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain259-381MsrB

Sequence similarities

Belongs to the MsrA Met sulfoxide reductase family.
Belongs to the MsrB Met sulfoxide reductase family.
In the C-terminal section; belongs to the MsrB Met sulfoxide reductase family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    397
  • Mass (Da)
    44,815
  • Last updated
    2017-07-05 v1
  • Checksum
    84D76F07464BA450
MKKLILAIVILLAAMFDLGMSMDQGMDKSGDAAMAARTAVFAGGCFWCTESDFEKVLGVSEVISGYTGGKEINPTYAQVSGHATGHVEAVKVTYDPAKVSYGQLVEWFWRHVDPTDNGGQFVDRGSQYRSVIFFADSEQRRIAEASKRRLAASGRFAAPIVTEILPLGPFYPAEDYHQDYHRKNPLRYGWYRSGSGRDQFLEKTWSDEELTFAAIVKEFPELRPKVSRTTKDNLKSSEEDMGMQQEGEKMNRRYMVPDDEELKKKLTPLQYKVTREDATERPFANSYWDNHEAGLYVDVISGEPLFSSSDKFESGTGWPSFTRPLEADNIVERKDGSLFMTRIEVRSRHADSHLGHVFPDGPAPTGLRYCINSAALRFIPKADLEKEGYGDYKELIK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
NAAD01000036
EMBL· GenBank· DDBJ
ORJ53684.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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