A0A1X0WI15 · A0A1X0WI15_9GAMM

  • Protein
    6-phosphogluconate dehydrogenase, decarboxylating
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO2, with concomitant reduction of NADP to NADPH.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 3/3.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site10-15NADP+ (UniProtKB | ChEBI)
Binding site33-35NADP+ (UniProtKB | ChEBI)
Binding site74-76NADP+ (UniProtKB | ChEBI)
Binding site102NADP+ (UniProtKB | ChEBI)
Binding site102substrate; ligand shared between dimeric partners; in other chain
Binding site128-130substrate; ligand shared between dimeric partners; in other chain
Active site183Proton acceptor
Binding site186-187substrate; ligand shared between dimeric partners; in other chain
Active site190Proton donor
Binding site191substrate; ligand shared between dimeric partners; in other chain
Binding site260substrate; ligand shared between dimeric partners; in other chain
Binding site287substrate; ligand shared between dimeric partners; in other chain
Binding site446substrate; ligand shared between dimeric partners
Binding site452substrate; ligand shared between dimeric partners

GO annotations

AspectTerm
Molecular FunctionNADP binding
Molecular Functionphosphogluconate dehydrogenase (decarboxylating) activity
Biological ProcessD-gluconate metabolic process
Biological Processorganic acid catabolic process
Biological Processpentose-phosphate shunt

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    6-phosphogluconate dehydrogenase, decarboxylating
  • EC number

Gene names

    • ORF names
      BS640_06090

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • DSM 100043
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Yersiniaceae > Rouxiella

Accessions

  • Primary accession
    A0A1X0WI15

Proteomes

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain179-4686-phosphogluconate dehydrogenase C-terminal

Sequence similarities

Belongs to the 6-phosphogluconate dehydrogenase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    469
  • Mass (Da)
    51,569
  • Last updated
    2017-07-05 v1
  • Checksum
    FD3875317566772B
MSKQQIGVVGMAVMGRNLALNIESRGYSVAIFNRSGDKTDEVVAENPGKNLVPYYTVEEFVESLEKPRRILLMVKAGEATDKTIASLTPHLDKGDILIDGGNTFYKDTIRRNKELSDQGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILEQIAARADDGDACVAYIGADGAGHYVKMVHNGIEYGDMQLIAEAYSLLKQSLNLSNEELATTFAEWNKGELSSYLIDITKDIFTKKDEAGNYLVDVILDEAANKGTGKWTSQSSLDLGEPLTLITESVFARYLSSLKDQRVAASKVLTGPAVKAFAGDKAEFIEKIRRALYLGKIVSYAQGFSQLKAASDENNWNLHYGEIAKIFRAGCIIRAQFLQKITDAYEENASIANLLLAPYFKNIADEYQQALRDVVSYAVQNGIPTPTFSAAINYYDSYRSAVLPANLIQAQRDYFGAHTYKRTDKEGVFHTEWLD

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MRWE01000007
EMBL· GenBank· DDBJ
ORJ26409.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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