A0A1X0WA58 · A0A1X0WA58_9GAMM

  • Protein
    Beta-barrel assembly-enhancing protease
  • Gene
    bepA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Features

Showing features for binding site, active site.

148750100150200250300350400450
TypeIDPosition(s)Description
Binding site135Zn2+ (UniProtKB | ChEBI); catalytic
Active site136
Binding site139Zn2+ (UniProtKB | ChEBI); catalytic
Binding site200Zn2+ (UniProtKB | ChEBI); catalytic
Active site204Proton donor

GO annotations

AspectTerm
Cellular Componentmembrane
Cellular Componentperiplasmic space
Molecular Functionmetalloendopeptidase activity
Molecular Functionzinc ion binding
Biological Processchaperone-mediated protein folding
Biological Processproteolysis involved in protein catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Beta-barrel assembly-enhancing protease
  • EC number

Gene names

    • Name
      bepA
    • ORF names
      BS640_20300

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • DSM 100043
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Yersiniaceae > Rouxiella

Accessions

  • Primary accession
    A0A1X0WA58

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for signal, chain.

TypeIDPosition(s)Description
Signal1-26
ChainPRO_501341532727-487Beta-barrel assembly-enhancing protease

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain70-258Peptidase M48

Sequence similarities

Belongs to the peptidase M48 family. BepA subfamily.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    487
  • Mass (Da)
    53,960
  • Last updated
    2017-07-05 v1
  • Checksum
    651A06785804D53B
MATRFVTTGLLVSTLSASLLPLYATADSADLLPDMGTTAGGTLTIDQELQMGDYYVRQLRGSAPLITDPLLDQYVNQLGNRLVAHAYSVRFPFHFFIVNNDELNAFAFFGGNVVLHSAIFRFTDNESELASVLSHEISHVTQRHLARAMEDQKSKSPLTWVGVLGSILLAMASPEAGMAGLTGTIAGTQQGMISFTRANEEEADRIGLQVLQRSGFDPEAMPNFLQKLADQSRYASKPPEMLLTHPLPDSRLSDARNRANQMPRIVVQSSEDFYFAKVRILGMYGTEDHPLTDDYLKQLSDGNIRQQSAAQYGRAVQFYKAKSFNQARNILEPMLKKDPGNAWYLDLLTDIDIDQKHVPQAIARLEKADAATSKDAVLQLNIANAYIEGGELAKASRLLYRYTYAHPDDVNGWDLLTKSVAEQGLRAQELAARAESMALVGRLDQSISMLSSASAQSKLGSLDQARYDARIDQLRQLQKRFQLYEKG

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MRWE01000046
EMBL· GenBank· DDBJ
ORJ23672.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp