A0A1X0P6H3 · A0A1X0P6H3_9TRYP
- Proteinleishmanolysin
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids974 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
Cofactor
Note: Binds 1 zinc ion per subunit.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 293 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
Active site | 294 | ||||
Binding site | 297 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
Binding site | 358 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | membrane | |
Molecular Function | metal ion binding | |
Molecular Function | metalloendopeptidase activity | |
Biological Process | cell adhesion | |
Biological Process | proteolysis |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameleishmanolysin
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Discoba > Euglenozoa > Kinetoplastea > Metakinetoplastina > Trypanosomatida > Trypanosomatidae > Trypanosoma
Accessions
- Primary accessionA0A1X0P6H3
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 924-950 | Helical | |||
Keywords
- Cellular component
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Signal | 1-16 | ||||
Chain | PRO_5012281229 | 17-974 | leishmanolysin | ||
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for compositional bias, region.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 42-56 | Polar residues | |||
Region | 42-119 | Disordered | |||
Compositional bias | 57-87 | Basic and acidic residues | |||
Compositional bias | 89-104 | Basic residues | |||
Compositional bias | 105-119 | Basic and acidic residues | |||
Sequence similarities
Belongs to the peptidase M8 family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length974
- Mass (Da)107,474
- Last updated2017-07-05 v1
- ChecksumB52811DDA6C3E837
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 42-56 | Polar residues | |||
Compositional bias | 57-87 | Basic and acidic residues | |||
Compositional bias | 89-104 | Basic residues | |||
Compositional bias | 105-119 | Basic and acidic residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
NBCO01000004 EMBL· GenBank· DDBJ | ORC92233.1 EMBL· GenBank· DDBJ | Genomic DNA |