A0A1X0NZ27 · A0A1X0NZ27_9TRYP

  • Protein
    Dihydroorotate dehydrogenase (fumarate)
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

FMN (UniProtKB | Rhea| CHEBI:58210 )

Pathway

Pyrimidine metabolism; UMP biosynthesis via de novo pathway.

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functiondihydroorotate dehydrogenase (fumarate) activity
Biological Process'de novo' pyrimidine nucleobase biosynthetic process
Biological Process'de novo' UMP biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Dihydroorotate dehydrogenase (fumarate)
  • EC number
  • Alternative names
    • Dihydroorotate oxidase

Gene names

    • ORF names
      TM35_000102120

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Edinburgh
  • Taxonomic lineage
    Eukaryota > Discoba > Euglenozoa > Kinetoplastea > Metakinetoplastina > Trypanosomatida > Trypanosomatidae > Trypanosoma

Accessions

  • Primary accession
    A0A1X0NZ27

Proteomes

Organism-specific databases

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain3-294Dihydroorotate dehydrogenase catalytic

Sequence similarities

Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    313
  • Mass (Da)
    33,875
  • Last updated
    2017-07-05 v1
  • Checksum
    1BF2299553CB89A0
MSLKVNILGHEFANPLMNAAGVLCSTIDDLQCMTASSSGSLVSKSCTTAHRDGNPEPRYCGLPLGSINSMGLPNLGFDVYLKYANEQHDYGRKPLFLSMSGLSAEENAAMCKRLAPVAKEKGVVLELNLSCPNVPGKPQVAYDFDTMRVYLKEVSEAYGLPFGVKMPPYFDIAHFDMAAAVLNEFPLVKFVTCVNSIGNGLVIDPATETVVIKPKQGFGGVGGKYILPTALANVNAFYRRCPDKLVFGCGGVYTGEDVFLHILAGASMVQVGTALHEEGPAIFDRLATELQEIMKKKGYKTLDEFRGRVKTIE

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
NBCO01000010
EMBL· GenBank· DDBJ
ORC89944.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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