A0A1X0NYV7 · A0A1X0NYV7_9TRYP
- ProteinKatanin p60 ATPase-containing subunit A1
- GeneKATNA1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids564 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays.
Catalytic activity
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | microtubule | |
Molecular Function | ATP binding | |
Molecular Function | ATP hydrolysis activity | |
Molecular Function | isomerase activity | |
Molecular Function | microtubule binding | |
Molecular Function | microtubule severing ATPase activity | |
Biological Process | microtubule severing |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameKatanin p60 ATPase-containing subunit A1
- EC number
- Short namesKatanin p60 subunit A1
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Discoba > Euglenozoa > Kinetoplastea > Metakinetoplastina > Trypanosomatida > Trypanosomatidae > Trypanosoma
Accessions
- Primary accessionA0A1X0NYV7
Proteomes
Organism-specific databases
Subcellular Location
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for compositional bias, region, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 96-135 | Polar residues | ||||
Sequence: VQLDRPPQESNAETTTAPSRAATTRPLRRTTVTNTNGANP | ||||||
Region | 96-249 | Disordered | ||||
Sequence: VQLDRPPQESNAETTTAPSRAATTRPLRRTTVTNTNGANPVAAARPAVMSVPPPMSTAARNEALYGDPDRFGPPRLKTPLRNSSPLARRRPVGGSLRAASPPRSTRPKAALPLQTQSQQTLRAGRTPAASSSAAVSSTNNNTTSRPRRQGARAT | ||||||
Compositional bias | 204-244 | Polar residues | ||||
Sequence: AALPLQTQSQQTLRAGRTPAASSSAAVSSTNNNTTSRPRRQ | ||||||
Domain | 312-449 | AAA+ ATPase | ||||
Sequence: PWKGVLLYGPPGTGKTMLAKAVASECNTTFFNISPATLTSKWRGDSEKLIRVLFEMARYYAPSTIFIDEIDSLCGQRGDGGEHEASRRAKGTLLAQMDGVGVDPGKIVMVLGATNHPWSIDEAMRRRLEKRIYIPLPD |
Sequence similarities
Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length564
- Mass (Da)61,971
- Last updated2017-07-05 v1
- ChecksumC2592586B355B470
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 96-135 | Polar residues | ||||
Sequence: VQLDRPPQESNAETTTAPSRAATTRPLRRTTVTNTNGANP | ||||||
Compositional bias | 204-244 | Polar residues | ||||
Sequence: AALPLQTQSQQTLRAGRTPAASSSAAVSSTNNNTTSRPRRQ |
Keywords
- Technical term