A0A1X0NY94 · A0A1X0NY94_9TRYP

  • Protein
    Leishmanolysin-like peptidase
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

  • Preference for hydrophobic residues at P1 and P1' and basic residues at P2' and P3'. A model nonapeptide is cleaved at -Ala-Tyr-|-Leu-Lys-Lys-.
    EC:3.4.24.36 (UniProtKB | ENZYME | Rhea)

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Features

Showing features for binding site, active site.

142550100150200250300350400
Type
IDPosition(s)Description
Binding site84Zn2+ (UniProtKB | ChEBI); catalytic
Active site85
Binding site88Zn2+ (UniProtKB | ChEBI); catalytic
Binding site153Zn2+ (UniProtKB | ChEBI); catalytic

GO annotations

AspectTerm
Cellular Componentcytoplasm
Cellular Componentmembrane
Molecular Functionmetal ion binding
Molecular Functionmetalloendopeptidase activity
Biological Processcell adhesion
Biological Processproteolysis

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Leishmanolysin-like peptidase
  • EC number

Gene names

    • ORF names
      TM35_000112100

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Edinburgh
  • Taxonomic lineage
    Eukaryota > Discoba > Euglenozoa > Kinetoplastea > Metakinetoplastina > Trypanosomatida > Trypanosomatidae > Trypanosoma

Accessions

  • Primary accession
    A0A1X0NY94

Proteomes

Organism-specific databases

Subcellular Location

PTM/Processing

Keywords

Family & Domains

Features

Showing features for region, compositional bias.

Type
IDPosition(s)Description
Region377-425Disordered
Compositional bias391-405Basic and acidic residues

Sequence similarities

Belongs to the peptidase M8 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    425
  • Mass (Da)
    47,206
  • Last updated
    2017-07-05 v1
  • Checksum
    02C85EAF789FCE38
GVIQIPKFKKGELCAPFTIPSEHHTTGISGADFVLYVAAGPSGGAAAWAGPCARLKNKRPIVGVMNYDPMFIDTADKSIRIVAHEIGHALGFGFTEMSMRNIVREAFKVRGKPYVTMVTSPLVQQMVRKHYGCPDAKGMELEDEGSSGTSLSHWERRNAKDELMVGLGGNLHYTAITMALFEDLGYYKADFSKAETMRWGKDAGCDFLRKPCFVDGVSPYPDMFCNQLKGNKSLLCTFDRLSLGFCTLSKYVQHLPQHFQYFKDPTLGGVGLLADFCPFVQEYVNGGCTNGEARAMLGSRIGPNSRCLKGNSLRMGTYSLGDVCVNTQCDKGTLRVQLLDDDTWYTCKEGEHITPSKVFTSGTILCPKYEEVCPEVTEDNNDAAPETSSETRSSKGDRNRTSSEKSSRQRSYPYRWNTRRRPRIE

Features

Showing features for non-terminal residue, compositional bias.

Type
IDPosition(s)Description
Non-terminal residue1
Compositional bias391-405Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
NBCO01000011
EMBL· GenBank· DDBJ
ORC89676.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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