A0A1X0NJH3 · A0A1X0NJH3_9TRYP

  • Protein
    ATP-dependent RNA helicase
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

RNA helicase.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentnucleolus
Molecular FunctionATP binding
Molecular Functionhydrolase activity
Molecular FunctionRNA binding
Molecular FunctionRNA helicase activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    ATP-dependent RNA helicase
  • EC number

Gene names

    • ORF names
      TM35_000431710

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Edinburgh
  • Taxonomic lineage
    Eukaryota > Discoba > Euglenozoa > Kinetoplastea > Metakinetoplastina > Trypanosomatida > Trypanosomatidae > Trypanosoma

Accessions

  • Primary accession
    A0A1X0NJH3

Proteomes

Organism-specific databases

Subcellular Location

Interaction

Subunit

eIF4F is a multi-subunit complex, the composition of which varies with external and internal environmental conditions. It is composed of at least EIF4A, EIF4E and EIF4G.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, motif, region.

Type
IDPosition(s)Description
Domain11-39DEAD-box RNA helicase Q
Motif11-39Q motif
Domain42-222Helicase ATP-binding
Region226-248Disordered
Domain268-476Helicase C-terminal
Region560-603Disordered

Domain

The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

Sequence similarities

Belongs to the DEAD box helicase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    603
  • Mass (Da)
    66,331
  • Last updated
    2017-07-05 v1
  • Checksum
    FB8BF73F6AF2E626
MTSSPSNVISTTWSELALDSRILEAVKRLHWETPTPVQSACIPLALKGRDLAVQSRTGSGKTAAFLIPILQRIITENEQMCNRRAGRNPAALILLPSVELCEQTVEVASALSKYVKPRIVVDNLTSRGAITKARLASAPILIATAALLGKQCRNGTLTAEEFKSLRCVVIDEVDLMMSIAESSVRAVQSILPPSIQTILCSATLTDAVAHIKGQLLHNPVTITLNTGDDDDDDNDDNNNGKNGSITTPGENLVVEARKIVRGGTADEKLQHYYLVATDECHHHTLLYSLYRLGHIKGKTLIFLSTEDAMYKLHSFLVQLGVDALVYDSNLPLNVRMDALHRFQIGSANTLVCTDGTLESIDRLQETSIGEGEVTTSTLNKKGKNTVSSDHIALQRGIDFSDVRNVILFDGITVPSTTAFSRYTHRVGRAGRAGKSGMAITLFSLQQAKKVTRPLREYLAKTQDPLQPFKQLQRRESAMLQYRVDNILASITRSSTRRQRIAAVATELTRSAYLNSHMSQKDGDALHRILSRSRKEVKCDSALLDVPHYMHIEKADSADHYRKRVSAKARSASATSRRSTKKTRDPLSSVASAVKMSATKKRRL

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
NBCO01000043
EMBL· GenBank· DDBJ
ORC84603.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help