A0A1W6SBI2 · A0A1W6SBI2_9PLVG
- ProteinReverse transcriptase
- Genepol
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids256 (go to sequence)
- Protein existencePredicted
- Annotation score1/5
Function
Catalytic activity
- Endohydrolysis of RNA in RNA/DNA hybrids. Three different cleavage modes: 1. sequence-specific internal cleavage of RNA. Human immunodeficiency virus type 1 and Moloney murine leukemia virus enzymes prefer to cleave the RNA strand one nucleotide away from the RNA-DNA junction. 2. RNA 5'-end directed cleavage 13-19 nucleotides from the RNA end. 3. DNA 3'-end directed cleavage 15-20 nucleotides away from the primer terminus.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | endonuclease activity | |
Molecular Function | RNA stem-loop binding | |
Molecular Function | RNA-directed DNA polymerase activity |
Keywords
- Molecular function
- Biological process
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Strain
- Taxonomic lineageViruses > Riboviria > Pararnavirae > Artverviricota > Revtraviricetes > Ortervirales > Retroviridae > Orthoretrovirinae > Lentivirus > Primate lentivirus group
Accessions
- Primary accessionA0A1W6SBI2
Structure
Sequence
- Sequence statusFragment
- Length256
- Mass (Da)29,737
- Last updated2017-07-05 v1
- MD5 Checksum6AD5BF26D3DD8ED2648C43A50D1E0965
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Non-terminal residue | 1 | ||||
Non-terminal residue | 256 | ||||
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
MF029851 EMBL· GenBank· DDBJ | ARO81354.1 EMBL· GenBank· DDBJ | Other RNA |