A0A1W6JSI0 · A0A1W6JSI0_9CAUD
- ProteinEndolysin
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids244 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.
Catalytic activity
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 20 | Proton donor/acceptor | |||
Active site | 29 | Proton donor/acceptor | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | host cell cytoplasm | |
Molecular Function | lysozyme activity | |
Biological Process | cell wall macromolecule catabolic process | |
Biological Process | defense response to bacterium | |
Biological Process | peptidoglycan catabolic process | |
Biological Process | viral release from host cell by cytolysis |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameEndolysin
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Taxonomic lineageViruses > Duplodnaviria > Heunggongvirae > Uroviricota > Caudoviricetes > Salasmaviridae > Harambevirus > Harambevirus harambe
Accessions
- Primary accessionA0A1W6JSI0
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Note: The endolysin is cytoplasmic, but can reach the periplasmic space with the help of the holins which disrupt the host cell membrane.
Keywords
- Cellular component
Structure
Sequence
- Sequence statusComplete
- Length244
- Mass (Da)27,636
- Last updated2017-07-05 v1
- Checksum7641DDFAE2F828AB
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
KY821088 EMBL· GenBank· DDBJ | ARM70175.1 EMBL· GenBank· DDBJ | Genomic DNA |