A0A1W5PVT2 · A0A1W5PVT2_NAJME

Function

function

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.

Catalytic activity

GO annotations

AspectTerm
Cellular Componentmitochondrial membrane
Cellular Componentrespiratory chain complex I
Molecular FunctionNADH dehydrogenase (ubiquinone) activity
Molecular FunctionNADH dehydrogenase activity
Molecular Functionubiquinone binding
Biological ProcessATP synthesis coupled electron transport
Biological Processelectron transport coupled proton transport

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADH-ubiquinone oxidoreductase chain 4
  • EC number

Gene names

    • Name
      ND4

Encoded on

  • Mitochondrion

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Lepidosauria > Squamata > Bifurcata > Unidentata > Episquamata > Toxicofera > Serpentes > Colubroidea > Elapidae > Elapinae > Naja

Accessions

  • Primary accession
    A0A1W5PVT2

Subcellular Location

Membrane
; Multi-pass membrane protein
Mitochondrion membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane23-43Helical
Transmembrane50-69Helical
Transmembrane75-96Helical
Transmembrane117-139Helical
Transmembrane159-178Helical

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-165NADH:quinone oxidoreductase/Mrp antiporter membrane subunit

Sequence similarities

Belongs to the complex I subunit 4 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    218
  • Mass (Da)
    24,190
  • Last updated
    2017-07-05 v1
  • Checksum
    7BF1C3946E37C053
LLKLGGYGIIRMSQTLPTMKTDVFLPFIVLSLWGATLASLTCLQQTDLKSLIAYSSISHMGLVIAAILIQTQWSLAGAMSMMVAHGFTSSALFCLANTTYERTKTRIMILTRGFHSILPMTTTWWLLANLMNIATPPSMNFTSELLIASSLFNWCPTSIILFGLLMLITATYSLHVFLSTQMNMPTLNTPIQPTHSREHLLMAMHIIPLILVSLKPEL

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1
Non-terminal residue218

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KX130765
EMBL· GenBank· DDBJ
APO14230.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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