A0A1W2PQL4 · ZN722_HUMAN
- ProteinZinc finger protein 722
- GeneZNF722
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids384 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
May be involved in transcriptional regulation.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | nucleus | |
Molecular Function | DNA-binding transcription factor activity, RNA polymerase II-specific | |
Molecular Function | metal ion binding | |
Molecular Function | RNA polymerase II cis-regulatory region sequence-specific DNA binding | |
Biological Process | regulation of DNA-templated transcription |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameZinc finger protein 722
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo
Accessions
- Primary accessionA0A1W2PQL4
Proteomes
Organism-specific databases
Subcellular Location
Disease & Variants
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 324 variants from UniProt as well as other sources including ClinVar and dbSNP.
Genetic variation databases
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000454666 | 1-384 | Zinc finger protein 722 | |||
Sequence: MAERPGSPGSREMRLLTFRDIAIEFSLEEWQCLDCAQQNLYRDVMLENYRNLVSLGIADSKPDLITCLEQNKEAWNIKRNEMVAKHPVTCSHFTQDLHPEQGIKHSLQKVIPRTYGKCGHENLQFKKCCKSVGECEVHKGGYNEVKQCLSNTQNKIFQTHKCVIVFGKFSNCNRHETRYTGKKHFKCKKYGKSFCMPSHLNQHQIIHTKEKSYKCEECGKSFKRSSNCTTHKRIHTGEKPYRCEECGKAFRWPSNLTRHKRIHTGEKPYTCEECGQAFRRSSTLTNHKRIHTGERPYKCEECGKAFSVSSTLNDHKRIHTGEKPYTCEECGRAFNCSSTLKTHKRIHTGEKPYKCEECDKAFKRHSSLAKHKIIHTGEKPYKSK |
Proteomic databases
Interaction
Miscellaneous
Structure
Family & Domains
Features
Showing features for domain, zinc finger.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 16-87 | KRAB | ||||
Sequence: LTFRDIAIEFSLEEWQCLDCAQQNLYRDVMLENYRNLVSLGIADSKPDLITCLEQNKEAWNIKRNEMVAKHP | ||||||
Zinc finger | 185-207 | C2H2-type 1; degenerate | ||||
Sequence: FKCKKYGKSFCMPSHLNQHQIIH | ||||||
Zinc finger | 213-235 | C2H2-type 2 | ||||
Sequence: YKCEECGKSFKRSSNCTTHKRIH | ||||||
Zinc finger | 241-263 | C2H2-type 3 | ||||
Sequence: YRCEECGKAFRWPSNLTRHKRIH | ||||||
Zinc finger | 269-291 | C2H2-type 4 | ||||
Sequence: YTCEECGQAFRRSSTLTNHKRIH | ||||||
Zinc finger | 297-319 | C2H2-type 5 | ||||
Sequence: YKCEECGKAFSVSSTLNDHKRIH | ||||||
Zinc finger | 325-347 | C2H2-type 6 | ||||
Sequence: YTCEECGRAFNCSSTLKTHKRIH | ||||||
Zinc finger | 353-375 | C2H2-type 7 | ||||
Sequence: YKCEECDKAFKRHSSLAKHKIIH |
Sequence similarities
Belongs to the krueppel C2H2-type zinc-finger protein family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length384
- Mass (Da)44,601
- Last updated2017-06-07 v1
- Checksum61FB6202CECB1A77
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AC092634 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AC115220 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |