A0A1W1ZPU0 · A0A1W1ZPU0_KIBAR

Function

function

Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Activity regulation

Inhibited by fructose 1,6-bisphosphate (FBP).

Pathway

Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site13ADP (UniProtKB | ChEBI)
Binding site13ATP (UniProtKB | ChEBI)
Binding site13sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site14ATP (UniProtKB | ChEBI)
Binding site15ATP (UniProtKB | ChEBI)
Binding site17ADP (UniProtKB | ChEBI)
Binding site83glycerol (UniProtKB | ChEBI)
Binding site83sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site84glycerol (UniProtKB | ChEBI)
Binding site84sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site135glycerol (UniProtKB | ChEBI)
Binding site135sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site241glycerol (UniProtKB | ChEBI)
Binding site241sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site242glycerol (UniProtKB | ChEBI)
Binding site263ADP (UniProtKB | ChEBI)
Binding site263ATP (UniProtKB | ChEBI)
Binding site307ADP (UniProtKB | ChEBI)
Binding site307ATP (UniProtKB | ChEBI)
Binding site311ATP (UniProtKB | ChEBI)
Binding site408ADP (UniProtKB | ChEBI)
Binding site408ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular FunctionATP binding
Molecular Functionglycerol kinase activity
Biological Processglycerol catabolic process
Biological Processglycerol-3-phosphate metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glycerol kinase
  • EC number
  • Alternative names
    • ATP:glycerol 3-phosphotransferase
    • Glycerokinase
      (GK
      )

Gene names

    • Name
      glpK
    • ORF names
      SAMN05661093_00236

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • DSM 43828
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Pseudonocardiales > Pseudonocardiaceae > Kibdelosporangium

Accessions

  • Primary accession
    A0A1W1ZPU0

Proteomes

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain5-248Carbohydrate kinase FGGY N-terminal
Domain257-446Carbohydrate kinase FGGY C-terminal

Sequence similarities

Belongs to the FGGY kinase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    626
  • Mass (Da)
    69,441
  • Last updated
    2017-06-07 v1
  • Checksum
    B248C65000E40BC9
MAQRYVMSIDQGTTSTRCILFDARGRLVSVVQREHQQYFPRPGWVEHDAAEIWRNLSKIVPDALAQAGATAEQVVGLGIANQRETTVLWDRRTGAPVGRAIVWQDTRTDRMIEQLEREPGAKRVRELCGLPLTTYFSAPKIRWMLDQTPGLQERAERGEVLFGTIESWLIWNLTGGLHVTDVTNASRTMLMNLRTLSWDAELLEFFDIPRAMLPEIRSSTEVYGTTTTVVPGIRIAAALGDQQAALFGQTCFAPGEAKCTYGTGSFLLLNTGQTPVLSKHGMLTTVGFKIGDEPAVYALEGSMAVTGSLVQWFRDGLELISSAPEIETLARTVQDNGGCYIVPAFSGLFAPHWHSEARGVIAGLTSYITKGHLARAVLEATGWQTREVVDAMNADSGLALSTLKVDGGMTADNLLMQFIADVLDVPVVRPMVAETVSLGAAYAAGLSVGYWPDLEGLRRNWHRAGQWLPAMAPTRRDTEYAQWRQAVELTFGWMRPAHDSRRPAGTDLIDVILDDHRQIEHLLRELRNEDTDRARVLSELSALLGAHFAATERILHKRVDISLDQDILDLEAAVEAHIRDEERTLLNELRRSLSPSDRTALGRAFTAESRNYAAIVRTRPTIPHDE

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FWXV01000001
EMBL· GenBank· DDBJ
SMC50071.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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