A0A1W1YJJ6 · A0A1W1YJJ6_9FIRM

Function

function

Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
K+ (UniProtKB | Rhea| CHEBI:29103 )

NH4+ (UniProtKB | Rhea| CHEBI:28938 )

K+ (UniProtKB | Rhea| CHEBI:29103 )

Note: A monovalent cation. Ammonium or potassium.

Pathway

Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 1/5.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site6-13ATP (UniProtKB | ChEBI)
Binding site105-108substrate
Active site107Proton acceptor
Binding site127K+ (UniProtKB | ChEBI)
Binding site130ATP (UniProtKB | ChEBI)
Binding site182substrate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular Functionpantothenate kinase activity
Biological Processcoenzyme A biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Type III pantothenate kinase
  • EC number
  • Alternative names
    • PanK-III
    • Pantothenic acid kinase

Gene names

    • Name
      coaX
    • ORF names
      SAMN02745168_0486

Organism names

Accessions

  • Primary accession
    A0A1W1YJJ6

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the type III pantothenate kinase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    270
  • Mass (Da)
    29,863
  • Last updated
    2017-06-07 v1
  • Checksum
    AFD2677276B1572C
MLLTVDVGNTNMVFTVYDGEQSIGSFRMSTNANRTSDEIGLWICDYFRRFELSIAEVEDVIIASVVPQVMYSLTSSIIKYINRTPIIVDEDVDPGLRYDVDGRLGVDRAVDCVAAIEKYGSPLIVLDFGTATTIDAVSENAEYLGGVILSGIRISLDALFTRAAMLPRVELVKPGHVLGKNTVEQMQAGAVCGYIGSVEYIVREMKSEMNAENIRVVATGGLGRLIAENTDEIDVFDPQLTPDGLRLVYEKYKREHRIKPRPKQSKSSKN

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FWXW01000001
EMBL· GenBank· DDBJ
SMC36400.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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