Essential maintenance is planned to begin on Fri Jan 24 2025. The website may be temporarily unavailable. Please use our fallback: https://wwwdev.ebi.ac.uk/uniprot/front-end/fallback/ in case of any outage.

A0A1W1WZR4 · A0A1W1WZR4_9NEIS

Function

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Features

Showing features for binding site.

163450100150200250300350400450500550600
TypeIDPosition(s)Description
Binding site333Zn2+ (UniProtKB | ChEBI); catalytic
Binding site384Zn2+ (UniProtKB | ChEBI); catalytic
Binding site510Zn2+ (UniProtKB | ChEBI); catalytic

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular Functionthreonine-tRNA ligase activity
Molecular FunctiontRNA binding
Biological Processthreonyl-tRNA aminoacylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Threonine--tRNA ligase
  • EC number
  • Alternative names
    • Threonyl-tRNA synthetase
      (ThrRS
      )

Gene names

    • Name
      thrS
    • ORF names
      SAMN02745857_00355

Organism names

  • Taxonomic identifier
  • Strain
    • DSM 23236
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Betaproteobacteria > Neisseriales > Chitinibacteraceae > Andreprevotia

Accessions

  • Primary accession
    A0A1W1WZR4

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, region.

Type
IDPosition(s)Description
Domain1-61TGS
Domain242-533Aminoacyl-transfer RNA synthetases class-II family profile
Region242-533Catalytic

Sequence similarities

Belongs to the class-II aminoacyl-tRNA synthetase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    634
  • Mass (Da)
    71,932
  • Last updated
    2017-06-07 v1
  • MD5 Checksum
    4F74EA6AAFE18CF9CDDA9F01F365A547
MPTITLPDGSQRQFDAPVTVAGVAASIGAGLARAALAGKVDGQLVDTSYLIDRDVQLAIVTERDADGLEVIRHSTAHLLAYAVKSLFPDAQVTIGPVIEDGFYYDFSYSRPFTPDDLEAIEKKMLELSKKDVPVERYELSRDEAIAYFKSIGEAYKAEIIESIPQDQVLSLYREGDFTDLCRGPHVPSTGKLKVFKLMKVAGAYWRGDSKNEMLTRIYGTAWAKKEDLEAYLHRLEESEKRDHRKIGRALDLFHMQEEAPGMVFWHPKGWSLWQSVEQYMRRRLNKAGYQEVRTPQMMDRSLWEKSGHWENYHDNMFVTESEKRTYAVKPMNCPGHVQIFNSDLRSYRDLPLRLAEFGACHRNEPTGSLHGLMRVRGFTQDDAHIFCMESQLIDEAKTFHALAMSVYEDFGFEGIQIKLALRPEKRAGEEAVWDRAEDGLREALRACGVEWVELPGEGAFYGPKIEYHIKDAIGRSWQCGTLQLDFVLPERLGPEYVAEDNTRQRPVMLHRAIVGSMERFLGILIENFSGAFPAWLAPTQAVVLNISESQREYAQNIAAQLKAAGVRAEADLRNEKITYKIREHSLQRVPYQLIVGDKEKEAGLVAVRSRSGEDLGQISLTAFMERLQAETPKD

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FWXD01000001
EMBL· GenBank· DDBJ
SMC17226.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help