A0A1V9BW05 · A0A1V9BW05_9BACI
- ProteinRiboflavin biosynthesis protein RibD
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids380 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
Catalytic activity
- 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + H2O + H+ = 5-amino-6-(5-phospho-D-ribosylamino)uracil + NH4+
Cofactor
Note: Binds 1 zinc ion.
Pathway
Cofactor biosynthesis; riboflavin biosynthesis; 5-amino-6-(D-ribitylamino)uracil from GTP: step 2/4.
Cofactor biosynthesis; riboflavin biosynthesis; 5-amino-6-(D-ribitylamino)uracil from GTP: step 3/4.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 51 | Zn2+ (UniProtKB | ChEBI); catalytic | ||||
Sequence: H | ||||||
Active site | 53 | Proton donor | ||||
Sequence: E | ||||||
Binding site | 76 | Zn2+ (UniProtKB | ChEBI); catalytic | ||||
Sequence: C | ||||||
Binding site | 85 | Zn2+ (UniProtKB | ChEBI); catalytic | ||||
Sequence: C | ||||||
Binding site | 155 | NADP+ (UniProtKB | ChEBI) | ||||
Sequence: A | ||||||
Binding site | 169 | NADP+ (UniProtKB | ChEBI) | ||||
Sequence: S | ||||||
Binding site | 171 | NADP+ (UniProtKB | ChEBI) | ||||
Sequence: W | ||||||
Binding site | 185 | substrate | ||||
Sequence: R | ||||||
Binding site | 197 | NADP+ (UniProtKB | ChEBI) | ||||
Sequence: T | ||||||
Binding site | 201 | NADP+ (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 205 | substrate | ||||
Sequence: L | ||||||
Binding site | 208 | substrate | ||||
Sequence: R | ||||||
Binding site | 223 | NADP+ (UniProtKB | ChEBI) | ||||
Sequence: T | ||||||
Binding site | 291 | substrate | ||||
Sequence: E | ||||||
Binding site | 293-299 | NADP+ (UniProtKB | ChEBI) | ||||
Sequence: GSRVHDS |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | 5-amino-6-(5-phosphoribosylamino)uracil reductase activity | |
Molecular Function | diaminohydroxyphosphoribosylaminopyrimidine deaminase activity | |
Molecular Function | NADP binding | |
Molecular Function | zinc ion binding | |
Biological Process | riboflavin biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameRiboflavin biosynthesis protein RibD
Including 2 domains:
- Recommended nameDiaminohydroxyphosphoribosylaminopyrimidine deaminase
- EC number
- Short namesDRAP deaminase
- Alternative names
- Recommended name5-amino-6-(5-phosphoribosylamino)uracil reductase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacillota > Bacilli > Bacillales > Bacillaceae > Geobacillus > Geobacillus thermoleovorans group
Accessions
- Primary accessionA0A1V9BW05
Proteomes
Structure
Sequence
- Sequence statusComplete
- Length380
- Mass (Da)40,710
- Last updated2017-06-07 v1
- ChecksumE04428C326E98DF8
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
NEWK01000001 EMBL· GenBank· DDBJ | OXB89749.1 EMBL· GenBank· DDBJ | Genomic DNA |