A0A1V9BMM1 · A0A1V9BMM1_9BACI

Function

function

Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

pyridoxal 5'-phosphate (UniProtKB | Rhea| CHEBI:597326 )

Pathway

Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; L-lysine from DL-2,6-diaminopimelate: step 1/1.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site248pyridoxal 5'-phosphate (UniProtKB | ChEBI)
Binding site290-293pyridoxal 5'-phosphate (UniProtKB | ChEBI)
Binding site293substrate
Binding site330substrate
Binding site334substrate
Active site361Proton donor
Binding site362substrate
Binding site390pyridoxal 5'-phosphate (UniProtKB | ChEBI)
Binding site390substrate

GO annotations

AspectTerm
Molecular Functiondiaminopimelate decarboxylase activity
Molecular Functionpyridoxal phosphate binding
Biological Processlysine biosynthetic process via diaminopimelate

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Diaminopimelate decarboxylase
  • EC number
  • Short names
    DAP decarboxylase
    ; DAPDC

Gene names

    • Name
      lysA
    • ORF names
      B9L19_06765

Organism names

  • Taxonomic identifier
  • Strain
    • BGSC 93A1
  • Taxonomic lineage
    Bacteria > Bacillota > Bacilli > Bacillales > Bacillaceae > Geobacillus > Geobacillus thermoleovorans group

Accessions

  • Primary accession
    A0A1V9BMM1

Proteomes

PTM/Processing

Features

Showing features for modified residue.

TypeIDPosition(s)Description
Modified residue66N6-(pyridoxal phosphate)lysine

Interaction

Subunit

Homodimer.

Family & Domains

Sequence similarities

Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    439
  • Mass (Da)
    47,897
  • Last updated
    2017-06-07 v1
  • Checksum
    BA8F504F1B75691D
MFLHGTSRVNEQGHLEIGGVDVVELAKTYGTPLYIYDVALIRARARAFKEAFQRHGVRAQVAYASKAFSAVAIVQLAAEEGLSLDVVSGGELYTALAAGFPPERIHFHGNNKSRDELAMALEHGIGCIVADNFYELELIEELAASSGRTVPVLLRVTPGVEAHTHDYILTGQEDSKFGFDLNNGQADEAFRRVMASAAFQLLGVHCHIGSQIFETAGFVLAAQKVFAKLAEWNKEHGFVPAVVNLGGGFGIRYTEEDDPIPVTAYVDCIVEEVKRQAEACRLPLPEIWIEPGRSLVGDAGTTIYTIGSRKEVPNVRTYIAVDGGMSDNIRPALYGAKYEAALANRVFGEPTEVVSIAGKCCESGDMLIWDIALPEAKPGDYLAVFCTGAYGYSMANNYNRLPRPAVVFVENGDAQLVVKRETYEDLIQYDLPLKTKVKK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
NEWK01000001
EMBL· GenBank· DDBJ
OXB89744.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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