A0A1V5M8U1 · A0A1V5M8U1_UNCT6

Function

function

Catalyzes the reduction of the glycolytic intermediate dihydroxyacetone phosphate (DHAP) to sn-glycerol 3-phosphate (G3P), the key precursor for phospholipid synthesis.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Membrane lipid metabolism; glycerophospholipid metabolism.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site8-13NAD+ (UniProtKB | ChEBI)
Binding site12NADPH (UniProtKB | ChEBI)
Binding site32NADPH (UniProtKB | ChEBI)
Binding site104NADPH (UniProtKB | ChEBI)
Binding site104sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site104substrate
Binding site132sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site134sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site136NAD+ (UniProtKB | ChEBI)
Binding site136NADPH (UniProtKB | ChEBI)
Active site187Proton acceptor
Binding site187sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site240sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site250sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site251NAD+ (UniProtKB | ChEBI)
Binding site251NADPH (UniProtKB | ChEBI)
Binding site251sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site251-252substrate
Binding site252sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site275NADPH (UniProtKB | ChEBI)
Binding site277NADPH (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionglycerol-3-phosphate dehydrogenase (NADP+) activity
Molecular Functionglycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Molecular FunctionNAD binding
Biological Processcarbohydrate metabolic process
Biological Processglycerol-3-phosphate biosynthetic process
Biological Processglycerol-3-phosphate catabolic process
Biological Processglycerophospholipid metabolic process
Biological Processphospholipid biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glycerol-3-phosphate dehydrogenase [NAD(P)+]
  • EC number
  • Alternative names
    • NAD(P)(+)-dependent glycerol-3-phosphate dehydrogenase
    • NAD(P)H-dependent dihydroxyacetone-phosphate reductase

Gene names

    • Name
      gpsA_1
    • Synonyms
      gpsA
    • ORF names
      BWY73_01462

Organism names

Accessions

  • Primary accession
    A0A1V5M8U1

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain3-155Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Domain176-316Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    327
  • Mass (Da)
    33,628
  • Last updated
    2017-06-07 v1
  • Checksum
    4C8BA85B363F307C
MEKIAVVGAGAWGTTLALLLAGPDRSVLLWEKFPDYARQLAGERENVKFLPGFELPENLDVTDDLALAASAPAVVLVTPSFACRETAGRLAAAGCRGPVLVATKGLEAGSGLRMSQVVAEAMPGVAWSVLSGPTIAREVAAGRPTAAVCAGPDEKLNFFFQDLFSTGHFRLYTSADAAGVEFGGALKNPLAIAAGIVEGLGLGDNAKATLLCRGLAEMARLGTALGGQERTFFGLSGLGDLITTACSPQSRNHRFGVAIGGGQPAGDYLKGQESVVEGYHSARPALKLAAGAGVEMPIISQVASVLFEGKPPAAAVRELMGRPLKAE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MWAK01000343
EMBL· GenBank· DDBJ
OPZ89654.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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