A0A1V5KCL4 · A0A1V5KCL4_9BACT

Function

function

Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Activity regulation

Na+ is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site77Na+ (UniProtKB | ChEBI); structural
Binding site80Na+ (UniProtKB | ChEBI); structural

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionfluoride channel activity
Molecular Functionmetal ion binding
Biological Processcellular detoxification of fluoride

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Fluoride-specific ion channel FluC

Gene names

    • Name
      crcB
    • Synonyms
      fluC
    • ORF names
      BWY84_00167

Organism names

Accessions

  • Primary accession
    A0A1V5KCL4

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane35-55Helical
Transmembrane67-85Helical
Transmembrane105-123Helical

Keywords

Family & Domains

Sequence similarities

Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    128
  • Mass (Da)
    13,762
  • Last updated
    2017-06-07 v1
  • Checksum
    C48632EEF4045779
MLGRILMVAFGGSLGAVSRYAVTHFVNLAFPGTVVSHWGTLTVNLAGSFLIGILFSTVQGVPHFNHLWLFFAVGFMGAFTTFSSYALEMHNQLAAGIYKDAALNFLLNNIGAVVMVFAGIFLVKMIKG

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MVZZ01000028
EMBL· GenBank· DDBJ
OPZ66489.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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