A0A1V5DFV4 · A0A1V5DFV4_9BACT
- ProteinBifunctional chorismate mutase/prephenate dehydratase
- GenepheA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids354 (go to sequence)
- Protein existencePredicted
- Annotation score3/5
Function
function
Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
Catalytic activity
- prephenate + H+ = 3-phenylpyruvate + CO2 + H2O
Pathway
Amino-acid biosynthesis; L-phenylalanine biosynthesis; phenylpyruvate from prephenate: step 1/1.
Metabolic intermediate biosynthesis; prephenate biosynthesis; prephenate from chorismate: step 1/1.
Features
Showing features for site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Site | 253 | Essential for prephenate dehydratase activity | ||||
Sequence: T |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | chorismate mutase activity | |
Molecular Function | prephenate dehydratase activity | |
Biological Process | chorismate metabolic process | |
Biological Process | L-phenylalanine biosynthetic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameBifunctional chorismate mutase/prephenate dehydratase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Thermodesulfobacteriota > Syntrophia > Syntrophales > Syntrophaceae > Syntrophus
Accessions
- Primary accessionA0A1V5DFV4
Proteomes
Subcellular Location
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 1-83 | Chorismate mutase | ||||
Sequence: MHLAEIRAEIDQTDMQIVKLINQRMEYVLRTGKLKQFILDPAREEQVLKQMLSQARGLIRPEFITELYQSIISESKLLQERNL | ||||||
Domain | 85-260 | Prephenate dehydratase | ||||
Sequence: LVGFQGEHGAWGELAVRRYAEDMIPIPCMEFAHVFEGVRDKELDFGMVPVENSLEGAVTEVNDILVETELNIAGEVVVPVRQCLLALPGTDYREIKVVYSHPQALAQCRSFLSRNKLEPRPFYDTAGAARWLSQERPSSTAVIASPIAAELYGLDVIKEDIGDNTDNFTRFLLISR | ||||||
Domain | 271-348 | ACT | ||||
Sequence: SLVFSTQHRAGALFEVLQVFAENEINLTRIESRPIRRNPGAYAFLLDFLGREDDPVVQKALGRIREMTPMSRILGYYP |
Family and domain databases
Sequence
- Sequence statusComplete
- Length354
- Mass (Da)40,048
- Last updated2017-06-07 v1
- Checksum2158F00B5A5F6CB3