A0A1V4U0M5 · A0A1V4U0M5_9EURY
- ProteinCRISPR-associated endonuclease Cas1
- Genecas1-2_2
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids327 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
Cofactor
Mn2+ (UniProtKB | Rhea| CHEBI:29035 )
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | DNA binding | |
Molecular Function | endonuclease activity | |
Molecular Function | metal ion binding | |
Biological Process | defense response to virus | |
Biological Process | maintenance of CRISPR repeat elements |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameCRISPR-associated endonuclease Cas1
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageArchaea > Euryarchaeota > Stenosarchaea group > Methanomicrobia > Methanomicrobiales > Methanoregulaceae
Accessions
- Primary accessionA0A1V4U0M5
Proteomes
Interaction
Subunit
Homodimer, forms a heterotetramer with a Cas2 homodimer.
Structure
Sequence
- Sequence statusComplete
- Length327
- Mass (Da)36,450
- Last updated2017-06-07 v1
- ChecksumB9BE3AC86862892A