A0A1V4U0G3 · A0A1V4U0G3_9EURY

Function

function

Catalyzes the transfer of diphosphate from ATP to 6-hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP).

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Pathway

Cofactor biosynthesis; 5,6,7,8-tetrahydromethanopterin biosynthesis.

GO annotations

AspectTerm
Molecular Function2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity
Molecular FunctionATP binding
Molecular Functionkinase activity
Molecular Functionmagnesium ion binding
Molecular Functionthiamine diphosphokinase activity
Biological Processphosphorylation
Biological Processtetrahydromethanopterin biosynthetic process
Biological Processthiamine diphosphate biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase
  • EC number
  • Short names
    HPPK
  • Alternative names
    • 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
    • 6-hydroxymethyl-7,8-dihydropterin diphosphokinase
      (6-HMPDK
      )
    • 7,8-dihydro-6-hydroxymethylpterin diphosphokinase
    • 7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase
      (PPPK
      )

Gene names

    • Name
      mptE
    • ORF names
      A4E36_02260

Organism names

Accessions

  • Primary accession
    A0A1V4U0G3

Proteomes

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain34-1826-hydroxymethylpterin diphosphokinase MptE-like

Sequence similarities

Belongs to the archaeal 6-HMPDK family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    204
  • Mass (Da)
    22,658
  • Last updated
    2017-06-07 v1
  • Checksum
    1D57A2980BDF752C
MNFDEWEPIYEEIVEYFGFDRKEDEDAADILEDLLERDDLDLLEETCRGHDVCVCGNAPCLVKEIPLVRGTVLAADAASLVLLSHGIRPDVIFTDLDGATDEFLDMNREGTIVVVHAHGDNIPLVRYWVPRFPGPLVGTTQSRPLPHVHNFGGFTDGDRAVFAAHSLGAAGITLLGFDLEDTRVDPMKRGKLYWAGRLLSLIEP

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MVQC01000134
EMBL· GenBank· DDBJ
OPX65978.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp