A0A1V4I2Q5 · A0A1V4I2Q5_NITVU

  • Protein
    Glycerol kinase
  • Gene
    glpK
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Activity regulation

Inhibited by fructose 1,6-bisphosphate (FBP).

Pathway

Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site12ADP (UniProtKB | ChEBI)
Binding site12ATP (UniProtKB | ChEBI)
Binding site12sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site13ATP (UniProtKB | ChEBI)
Binding site14ATP (UniProtKB | ChEBI)
Binding site16ADP (UniProtKB | ChEBI)
Binding site82glycerol (UniProtKB | ChEBI)
Binding site82sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site83glycerol (UniProtKB | ChEBI)
Binding site83sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site134glycerol (UniProtKB | ChEBI)
Binding site134sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site243glycerol (UniProtKB | ChEBI)
Binding site243sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site244glycerol (UniProtKB | ChEBI)
Binding site265ADP (UniProtKB | ChEBI)
Binding site265ATP (UniProtKB | ChEBI)
Binding site308ADP (UniProtKB | ChEBI)
Binding site308ATP (UniProtKB | ChEBI)
Binding site312ATP (UniProtKB | ChEBI)
Binding site412ADP (UniProtKB | ChEBI)
Binding site412ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular FunctionATP binding
Molecular Functionglycerol kinase activity
Biological Processglycerol catabolic process
Biological Processglycerol-3-phosphate metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glycerol kinase
  • EC number
  • Alternative names
    • ATP:glycerol 3-phosphotransferase
    • Glycerokinase
      (GK
      )

Gene names

    • Name
      glpK
    • ORF names
      B2M20_01535

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Ab1
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Alphaproteobacteria > Hyphomicrobiales > Nitrobacteraceae > Nitrobacter

Accessions

  • Primary accession
    A0A1V4I2Q5

Proteomes

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain5-250Carbohydrate kinase FGGY N-terminal
Domain261-451Carbohydrate kinase FGGY C-terminal

Sequence similarities

Belongs to the FGGY kinase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    500
  • Mass (Da)
    54,027
  • Last updated
    2017-06-07 v1
  • Checksum
    39E7C07744C8FE08
METHILAIDQGTTSSRAIVFRADISIAAIAQQEFPQHFPASGWVEHEPEDIWTSTVATCRQAMKKAGVTPKDIAAIGITNQRETTVVWDRATGKAVHRAIVWQDRRTADICARLKAEGHEPAISAKTGLIIDPYFSGTKVAWILDSVPGARARAMRGELMFGTVDCYLLWRLTGGKVHATDATNASRTLLFNIHTGQWDDELLDMLQVPRAMLPEVKDSSLHFGDSAPELFGAPISIRGIAGDQQAAVVGQACFAPGMIKSTYGTGCFALLNTGTTPVASNNKLLTTIAYQLNGQRTYALEGSIFVAGSAVQWLRDGLGLIKQASDTGPLAEQSDPTQSVYLVPAFVGMGAPYWKPNVRGALFGLTRNTGPAELAHAALESVCYQTFDLWDAMRADWPGADAAHTVLRVDGGMTASDWTMQRLADLLEAPVDRPVIQETTALGAAYLAGLSAGVYPEPSRFADSWRLERRFRPAMSAATRTRKLKGWAAAVRGVLASDEQ

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MWPQ01000004
EMBL· GenBank· DDBJ
OPH84507.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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