A0A1V1FIF9 · A0A1V1FIF9_MUSSB

Function

function

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.

Catalytic activity

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmitochondrial inner membrane
Molecular FunctionNADH dehydrogenase (ubiquinone) activity
Molecular FunctionNADH dehydrogenase activity
Biological ProcessATP synthesis coupled electron transport
Biological Processelectron transport coupled proton transport

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADH-ubiquinone oxidoreductase chain 5
  • EC number

Gene names

    • Name
      ND5

Encoded on

  • Mitochondrion

Organism names

  • Taxonomic identifier
  • Strains
    • SB02
    • SB03
    • SB04
    • SB05
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Carnivora > Caniformia > Musteloidea > Mustelidae > Mustelinae > Mustela

Accessions

  • Primary accession
    A0A1V1FIF9

Subcellular Location

Mitochondrion inner membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane6-31Helical
Transmembrane43-61Helical
Transmembrane87-108Helical
Transmembrane120-137Helical
Transmembrane143-163Helical
Transmembrane175-194Helical
Transmembrane248-266Helical
Transmembrane278-297Helical
Transmembrane365-389Helical
Transmembrane409-436Helical
Transmembrane457-476Helical
Transmembrane488-509Helical
Transmembrane585-607Helical

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain71-121NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Domain137-421NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Domain425-604NADH dehydrogenase subunit 5 C-terminal

Sequence similarities

Belongs to the complex I subunit 5 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    609
  • Mass (Da)
    68,725
  • Last updated
    2017-06-07 v1
  • Checksum
    5990F23503E9FCC6
MKVINLLTSSVLVTLLMLTFPIMMTSTTMYANKSYPQYVKTTTSYAFMISLIPTMMFLHLGQDTMISNWHWITIQTMKLSLSFKLDYFSMIFMPVALFVTWSIMEFSMWYMHSDPNINRFFKYLLLFLITMMILVTANNMFQLFIGWEGVGIMSFLLIGWWYGRTDANTAALQAILYNRIGDVGFILAMAWFLTNLNTWDLQQIFMTSNENLTIPLAGLLLAATGKSAQFGLHPWLPSAMEGPTPVSALLHSSTMVVAGVFLLIRFHPLMEYNKTIQTITLCLGAITTLFTAICALTQNDIKKIVAFSTSSQLGLMMVTIGINQPYLAFLHICTHAFFKAMLFMCSGSIIHSLNDEQDIRKMGGLFKALPFTTTSLIVGSLALTGMPFLTGFYSKDLIIETANTSCTNAWALLLTLVATSMTAAYSTRIMFFALLGQPRFNPIITINENNPLLINSIKRLLFGSIFAGFLISHNLTPTTTPQMTMPHYLKMMALAVTILGFILALELNLTMQSLKFKYPTNLFKFSNMLGYFPTIIHRLMPKTNLLMSQKSASTLLDMIWLEKILPKSISHFQMKSSMTISSQKGLIKLYFMSFMLTLALSLLTLNFHE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AP017413
EMBL· GenBank· DDBJ
BAX03299.1
EMBL· GenBank· DDBJ
Genomic DNA
AP017414
EMBL· GenBank· DDBJ
BAX03312.1
EMBL· GenBank· DDBJ
Genomic DNA
AP017415
EMBL· GenBank· DDBJ
BAX03325.1
EMBL· GenBank· DDBJ
Genomic DNA
AP017416
EMBL· GenBank· DDBJ
BAX03338.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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