A0A1T1AMV1 · A0A1T1AMV1_RHOFE
- ProteinUridylate kinase
- GenepyrH
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids240 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the reversible phosphorylation of UMP to UDP.
Catalytic activity
- ATP + UMP = ADP + UDP
Activity regulation
Inhibited by UTP.
Pathway
Pyrimidine metabolism; CTP biosynthesis via de novo pathway; UDP from UMP (UMPK route): step 1/1.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 14-17 | ATP (UniProtKB | ChEBI) | ||||
Sequence: KLSG | ||||||
Binding site | 56 | UMP (UniProtKB | ChEBI) | ||||
Sequence: G | ||||||
Binding site | 57 | ATP (UniProtKB | ChEBI) | ||||
Sequence: G | ||||||
Binding site | 61 | ATP (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Binding site | 76 | UMP (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 137-144 | UMP (UniProtKB | ChEBI) | ||||
Sequence: TGNPFFTT | ||||||
Binding site | 164 | ATP (UniProtKB | ChEBI) | ||||
Sequence: T | ||||||
Binding site | 170 | ATP (UniProtKB | ChEBI) | ||||
Sequence: Y | ||||||
Binding site | 173 | ATP (UniProtKB | ChEBI) | ||||
Sequence: D |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | UMP kinase activity | |
Biological Process | 'de novo' CTP biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameUridylate kinase
- EC number
- Short namesUK
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Comamonadaceae > Rhodoferax
Accessions
- Primary accessionA0A1T1AMV1
Proteomes
Subcellular Location
Interaction
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 9-218 | Aspartate/glutamate/uridylate kinase | ||||
Sequence: KRILLKLSGEALMGDDQFGINRNTIVRMVDEIVEVTRLGVEVAVVIGGGNIFRGVAGGSVGMDRATADYMGMLATVMNSLALGDTMNKAGLTARVMSAIAIEQVVEPYVRPKALQYLEEGKVVIFAAGTGNPFFTTDTAAALRGAEIGAQIVLKATKVDGVYSADPKKDPTATRYSKISFDDAISQNLGIMDATAFALCRDQKLPIKVFS |
Sequence similarities
Belongs to the UMP kinase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length240
- Mass (Da)25,549
- Last updated2017-05-10 v1
- Checksum7B4DD5E3FA3F13AC
Keywords
- Technical term