A0A1S9BVR4 · A0A1S9BVR4_9FIRM
- ProteintRNA pseudouridine synthase B
- GenetruB
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids530 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
function
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
Catalytic activity
- FMN + ATP + H+ = FAD + diphosphate
Pathway
Cofactor biosynthesis; FAD biosynthesis; FAD from FMN: step 1/1.
Cofactor biosynthesis; FMN biosynthesis; FMN from riboflavin (ATP route): step 1/1.
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 38 | Nucleophile | ||||
Sequence: D |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | ATP binding | |
Molecular Function | FMN adenylyltransferase activity | |
Molecular Function | riboflavin kinase activity | |
Molecular Function | RNA binding | |
Molecular Function | tRNA pseudouridine(55) synthase activity | |
Biological Process | FAD biosynthetic process | |
Biological Process | FMN biosynthetic process | |
Biological Process | mRNA pseudouridine synthesis | |
Biological Process | riboflavin biosynthetic process | |
Biological Process | tRNA pseudouridine synthesis |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nametRNA pseudouridine synthase B
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacillota > Clostridia > Lachnospirales > Lachnospiraceae > Oribacterium
Accessions
- Primary accessionA0A1S9BVR4
Proteomes
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 402-528 | Riboflavin kinase | ||||
Sequence: LLGRHVSLSGTVVYGKQIGSTILGFPTANLLPKEGKTIPKAGVYVSRVLVGQDLYRGMTNVGTNPTVSDGNPVDVETFIIGFNGDIYGKKIRVEFMDRLRDQEKFPSLEELKKQLEKDVERAAHYPM |
Sequence similarities
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length530
- Mass (Da)58,808
- Last updated2017-05-10 v1
- Checksum51200ADAE553441A
Keywords
- Technical term