A0A1S7UHF9 · A0A1S7UHF9_ROSNE
- ProteinCarbamoyl phosphate synthase arginine-specific small chain
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids460 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- 2 ATP + H2O + hydrogencarbonate + L-glutamine = 2 ADP + carbamoyl phosphate + 2 H+ + L-glutamate + phosphate
- H2O + L-glutamine = L-glutamate + NH4+
Pathway
Amino-acid biosynthesis; L-arginine biosynthesis; carbamoyl phosphate from bicarbonate: step 1/1.
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 316 | Nucleophile | ||||
Sequence: C | ||||||
Active site | 400 | |||||
Sequence: H | ||||||
Active site | 402 | |||||
Sequence: E |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | ATP binding | |
Molecular Function | carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity | |
Molecular Function | glutaminase activity | |
Biological Process | 'de novo' pyrimidine nucleobase biosynthetic process | |
Biological Process | glutamine metabolic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameCarbamoyl phosphate synthase arginine-specific small chain
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Sordariomycetes > Xylariomycetidae > Xylariales > Xylariaceae > Rosellinia
Accessions
- Primary accessionA0A1S7UHF9
Proteomes
Interaction
Subunit
Heterodimer composed of 2 chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 36-62 | Disordered | ||||
Sequence: TKPKGSKGRQMPSKYSPSTPRASGNEA | ||||||
Compositional bias | 46-61 | Polar residues | ||||
Sequence: MPSKYSPSTPRASGNE | ||||||
Domain | 60-199 | Carbamoyl-phosphate synthase small subunit N-terminal | ||||
Sequence: NEATLTLRDGPVFHGKAFGANSNISGEAVFTTALVGYPESMTDPSYRGQILVFTQPLIGNYGVPAPVRDEWNLLRHFESPHIQCAGIVVADAAEKYSHWTAVESLGDWCAREGIPAISGVDTRAIVTYLREQGSSLARIS |
Sequence similarities
Belongs to the CarA family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length460
- Mass (Da)50,127
- Last updated2017-05-10 v1
- ChecksumBEBCDB987DEA74D6
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 46-61 | Polar residues | ||||
Sequence: MPSKYSPSTPRASGNE |
Keywords
- Technical term