A0A1S7IVA9 · A0A1S7IVA9_9VIRU
- ProteinNon-structural polyprotein 1AB
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids1352 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Responsible for the cleavage of the polyprotein into functional products.
Catalytic activity
- RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | host cell membrane | |
Cellular Component | membrane | |
Molecular Function | hydrolase activity | |
Molecular Function | nucleotide binding | |
Molecular Function | RNA binding | |
Molecular Function | RNA-dependent RNA polymerase activity | |
Biological Process | DNA-templated transcription | |
Biological Process | viral RNA genome replication | |
Biological Process | viral translational frameshifting |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameNon-structural polyprotein 1AB
Organism names
- Organism
- Strains
- Taxonomic lineageViruses > Riboviria > Orthornavirae > Pisuviricota > Stelpaviricetes > Stellavirales > Astroviridae
Accessions
- Primary accessionA0A1S7IVA9
Subcellular Location
UniProt Annotation
GO Annotation
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 136-156 | Helical | ||||
Sequence: IFLYAFVVGLLVSSLPMSHAW | ||||||
Transmembrane | 245-274 | Helical | ||||
Sequence: LWFFSSLTFLFQSYGTSNWLVASLIVILSL | ||||||
Transmembrane | 295-328 | Helical | ||||
Sequence: WVHLVLMLVSLFDALGALFLSLLYLFCAPLVYLW |
Keywords
- Cellular component
Interaction
Subunit
Monomer.
Structure
Family & Domains
Features
Showing features for coiled coil, compositional bias, region, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Coiled coil | 85-112 | |||||
Sequence: VSVALLENARLKEQVKDLQSKNSQAALE | ||||||
Coiled coil | 586-646 | |||||
Sequence: ISKVQEKDREIEKLKAELEALRTQPSLQQSDCPQEVVDLVREAVRQEMLRLRLEFAQAKGK | ||||||
Compositional bias | 737-754 | Basic and acidic residues | ||||
Sequence: PAEPDQALRDEPNEEKKK | ||||||
Region | 737-759 | Disordered | ||||
Sequence: PAEPDQALRDEPNEEKKKPGPFQ | ||||||
Region | 836-855 | Disordered | ||||
Sequence: RKMRHPKPRQQPKNLPTDPS | ||||||
Domain | 1099-1224 | RdRp catalytic | ||||
Sequence: RYWVEVDWTRYDGTIPQQLLRIIRQVRWEFLDDVYKTAENRKLYEWYVHNLLNRYVLLPSGEVTFQDRGNPSGQVSTSVDNGMVNYYLQAYEHYVLNGPDGWEDTDTLIYGDDRLSVTNFPPDPEE |
Sequence similarities
Belongs to the astroviridae polyprotein 1AB family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,352
- Mass (Da)155,160
- Last updated2017-05-10 v1
- Checksum28C8167A757D1D21
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 737-754 | Basic and acidic residues | ||||
Sequence: PAEPDQALRDEPNEEKKK |
Keywords
- Coding sequence diversity