A0A1S7C4X4 · A0A1S7C4X4_CITMA
- ProteinAcetyl-coenzyme A carboxylase carboxyl transferase subunit beta
- GeneaccD
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids492 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO2 group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
Catalytic activity
- N6-carboxybiotinyl-L-lysyl-[protein] + acetyl-CoA = N6-biotinyl-L-lysyl-[protein] + malonyl-CoA
Cofactor
Note: Binds 1 zinc ion per subunit.
Pathway
Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 232 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 235 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 251 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 254 | Zn2+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | acetyl-CoA carboxylase complex | |
Cellular Component | chloroplast | |
Molecular Function | acetyl-CoA carboxylase activity | |
Molecular Function | ATP binding | |
Molecular Function | carboxyl- or carbamoyltransferase activity | |
Molecular Function | zinc ion binding | |
Biological Process | fatty acid biosynthetic process | |
Biological Process | malonyl-CoA biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAcetyl-coenzyme A carboxylase carboxyl transferase subunit beta
- EC number
- Short namesACCase subunit beta ; Acetyl-CoA carboxylase carboxyltransferase subunit beta
Gene names
Encoded on
- Plastid
Organism names
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Sapindales > Rutaceae > Aurantioideae > Citrus
Accessions
- Primary accessionA0A1S7C4X4
Subcellular Location
UniProt Annotation
GO Annotation
Keywords
- Cellular component
Interaction
Subunit
Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein, biotin carboxylase and 2 subunits each of ACCase subunit alpha and ACCase plastid-coded subunit beta (accD).
Structure
Family & Domains
Features
Showing features for region, domain, zinc finger.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 198-219 | Disordered | |||
Domain | 228-492 | CoA carboxyltransferase N-terminal | |||
Zinc finger | 232-254 | C4-type | |||
Sequence similarities
Belongs to the AccD/PCCB family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length492
- Mass (Da)55,372
- Last updated2017-05-10 v1
- MD5 ChecksumC1698604B4515D727A00392E002D4F9E
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
KY055833 EMBL· GenBank· DDBJ | AQX91127.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MN782007 EMBL· GenBank· DDBJ | QMJ95569.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MW770450 EMBL· GenBank· DDBJ | QXL58795.1 EMBL· GenBank· DDBJ | Genomic DNA |