A0A1S7B8K4 · A0A1S7B8K4_9MICO

  • Protein
    Uridylate kinase
  • Gene
    pyrH
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the reversible phosphorylation of UMP to UDP.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Activity regulation

Inhibited by UTP.

Pathway

Pyrimidine metabolism; CTP biosynthesis via de novo pathway; UDP from UMP (UMPK route): step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site11-14ATP (UniProtKB | ChEBI)
Binding site51UMP (UniProtKB | ChEBI)
Binding site52ATP (UniProtKB | ChEBI)
Binding site56ATP (UniProtKB | ChEBI)
Binding site71UMP (UniProtKB | ChEBI)
Binding site132-139UMP (UniProtKB | ChEBI)
Binding site160ATP (UniProtKB | ChEBI)
Binding site166ATP (UniProtKB | ChEBI)
Binding site169ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular FunctionUMP kinase activity
Biological Process'de novo' CTP biosynthetic process
Biological ProcessUDP biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Uridylate kinase
  • EC number
  • Short names
    UK
  • Alternative names
    • Uridine monophosphate kinase
      (UMP kinase
      ; UMPK
      )

Gene names

    • Name
      pyrH
    • ORF names
      EDD42_1569

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • DSM 14012
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Micrococcales > Microbacteriaceae > Plantibacter

Accessions

  • Primary accession
    A0A1S7B8K4

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homohexamer.

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the UMP kinase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    237
  • Mass (Da)
    24,850
  • Last updated
    2017-05-10 v1
  • Checksum
    4DFE7E70F5A1A04D
MPEKKRRVLLKLSGEAFGGGQLGVNPDVVGSIAREIAEATAEVEVAVVVGGGNFFRGAELSQRGMDRGRADYMGMLGTVMNALALQDFLEQAGAATRVQSAIAMTQVAEPYIPLRAERHLEKGRVVIFGAGAGLPYFSTDTVSAQRALEIGAVEVLVAKNGVDGVYTADPRVDPTATKIDTISYQEALQRGLKVVDSTAFSLCMDNGMPMRVFGMEPAGNVTAAIRGAAIGTLVTSA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
RKHL01000001
EMBL· GenBank· DDBJ
ROR81507.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp