A0A1S5WIV3 · A0A1S5WIV3_9VIRI
- ProteinClathrin light chain
- GeneCLC2a
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids272 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score2/5
Function
function
Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | clathrin coat of coated pit | |
Cellular Component | clathrin coat of trans-Golgi network vesicle | |
Molecular Function | clathrin heavy chain binding | |
Molecular Function | structural molecule activity | |
Biological Process | clathrin-dependent endocytosis | |
Biological Process | intracellular protein transport |
Names & Taxonomy
Protein names
- Recommended nameClathrin light chain
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Charophyceae > Charales > Characeae > Chara
Accessions
- Primary accessionA0A1S5WIV3
Subcellular Location
UniProt Annotation
GO Annotation
Cytoplasmic vesicle membrane ; Peripheral membrane protein
Membrane, coated pit ; Peripheral membrane protein
Note: Cytoplasmic face of coated pits and vesicles.
Keywords
- Cellular component
Structure
Family & Domains
Features
Showing features for region, compositional bias, coiled coil.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-50 | Disordered | ||||
Sequence: MSEEQVEDDASGSGSGNGDGKENMSPMGTGGTPTSARTLPRRESSTVLRE | ||||||
Compositional bias | 7-42 | Polar residues | ||||
Sequence: EDDASGSGSGNGDGKENMSPMGTGGTPTSARTLPRR | ||||||
Coiled coil | 55-83 | |||||
Sequence: IHEWRRQRAKELQKKADMEKKKKADILQQ | ||||||
Compositional bias | 142-165 | Basic and acidic residues | ||||
Sequence: VGAEEKEKPARAGSVDRGKDKGRR | ||||||
Region | 142-194 | Disordered | ||||
Sequence: VGAEEKEKPARAGSVDRGKDKGRRGSGAASSPSTSTSAGSPAALPKPGDWQAR | ||||||
Compositional bias | 168-182 | Polar residues | ||||
Sequence: GAASSPSTSTSAGSP |
Sequence similarities
Belongs to the clathrin light chain family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length272
- Mass (Da)29,994
- Last updated2017-05-10 v1
- ChecksumCFA7CC4CAEA17A0C
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 7-42 | Polar residues | ||||
Sequence: EDDASGSGSGNGDGKENMSPMGTGGTPTSARTLPRR | ||||||
Compositional bias | 142-165 | Basic and acidic residues | ||||
Sequence: VGAEEKEKPARAGSVDRGKDKGRR | ||||||
Compositional bias | 168-182 | Polar residues | ||||
Sequence: GAASSPSTSTSAGSP |