A0A1S4GYH9 · D7R3_ANOGA
- ProteinShort form salivary protein D7R3
- GeneD7r3
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids169 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
function
Modulates blood feeding of female mosquitoes on vertebrate species by binding and sequestering different mediators involved in the host response (By similarity).
Binds serotonin, noradrenaline, histamine and adrenaline (PubMed:16301315).
Inhibits histamine-, serotonin- and noradrenaline-induced smooth muscle contraction (PubMed:16301315).
Exhibits vasodilating activity (PubMed:16301315).
Binds serotonin, noradrenaline, histamine and adrenaline (PubMed:16301315).
Inhibits histamine-, serotonin- and noradrenaline-induced smooth muscle contraction (PubMed:16301315).
Exhibits vasodilating activity (PubMed:16301315).
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 31 | noradrenaline (UniProtKB | ChEBI) | |||
Binding site | 31 | serotonin (UniProtKB | ChEBI) | |||
Binding site | 46 | noradrenaline (UniProtKB | ChEBI) | |||
Binding site | 59 | serotonin (UniProtKB | ChEBI) | |||
Binding site | 118 | histamine (UniProtKB | ChEBI) | |||
Binding site | 118 | serotonin (UniProtKB | ChEBI) | |||
Binding site | 135 | histamine (UniProtKB | ChEBI) | |||
Binding site | 135 | noradrenaline (UniProtKB | ChEBI) | |||
Binding site | 135 | serotonin (UniProtKB | ChEBI) | |||
Binding site | 138 | histamine (UniProtKB | ChEBI) | |||
Binding site | 138 | noradrenaline (UniProtKB | ChEBI) | |||
Binding site | 138 | serotonin (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | extracellular region | |
Molecular Function | odorant binding | |
Biological Process | vasodilation |
Keywords
- Molecular function
Names & Taxonomy
Protein names
- Recommended nameShort form salivary protein D7R3
- Alternative names
Gene names
Organism names
- Strains
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Nematocera > Culicoidea > Culicidae > Anophelinae > Anopheles
Accessions
- Primary accessionA0A1S4GYH9
- Secondary accessions
Proteomes
Organism-specific databases
Subcellular Location
PTM/Processing
Features
Showing features for signal, chain, disulfide bond.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Signal | 1-21 | ||||
Chain | PRO_5010148875 | 22-169 | Short form salivary protein D7R3 | ||
Disulfide bond | 30↔62 | ||||
Disulfide bond | 43↔168 | ||||
Disulfide bond | 101↔120 | ||||
Keywords
- PTM
Structure
Sequence
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
- Length169
- Mass (Da)18,636
- Last updated2017-04-12 v1
- Checksum405024C44F8924E1
Features
Showing features for sequence conflict.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Sequence conflict | 12 | in Ref. 1; AAK84943/CAB39729 and 3; CAA03871 | |||
Sequence conflict | 40 | in Ref. 1; AAK84943/CAB39729 and 3; CAA03871 | |||
Sequence conflict | 96 | in Ref. 1; AAK84943/CAB39729 and 3; CAA03871 | |||
Sequence conflict | 103 | in Ref. 3; CAA03871 | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AJ133854 EMBL· GenBank· DDBJ | CAB39729.1 EMBL· GenBank· DDBJ | mRNA | ||
AY045760 EMBL· GenBank· DDBJ | AAK84943.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAAB01008964 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AJ000035 EMBL· GenBank· DDBJ | CAA03871.1 EMBL· GenBank· DDBJ | mRNA |