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A0A1S3EKB5 · A0A1S3EKB5_DIPOR

Function

Catalytic activity

Features

Showing features for binding site.

151250100150200250300350400450500
TypeIDPosition(s)Description
Binding site275ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentextrinsic component of cytoplasmic side of plasma membrane
Cellular ComponentGolgi apparatus
Cellular Componentmembrane raft
Cellular Componentnucleus
Cellular Componentperinuclear region of cytoplasm
Cellular Componentprotein-containing complex
Molecular FunctionATP binding
Molecular Functionephrin receptor binding
Molecular Functionnon-membrane spanning protein tyrosine kinase activity
Molecular Functionphosphatidylinositol 3-kinase activator activity
Molecular Functionphosphorylation-dependent protein binding
Molecular Functionprotein-containing complex binding
Molecular Functionscaffold protein binding
Molecular FunctionSH3 domain binding
Molecular Functiontransmembrane transporter binding
Biological Processautophagy
Biological ProcessB cell homeostasis
Biological ProcessB cell receptor signaling pathway
Biological ProcessC-X-C chemokine receptor CXCR4 signaling pathway
Biological Processcell morphogenesis
Biological Processcell surface receptor protein tyrosine kinase signaling pathway
Biological Processcellular response to retinoic acid
Biological Processdendritic cell differentiation
Biological ProcessDNA damage checkpoint signaling
Biological Processeosinophil differentiation
Biological Processerythrocyte differentiation
Biological Processfatty acid transport
Biological ProcessFc receptor mediated inhibitory signaling pathway
Biological ProcessFc receptor mediated stimulatory signaling pathway
Biological Processhematopoietic progenitor cell differentiation
Biological Processinnate immune response
Biological Processinterleukin-5-mediated signaling pathway
Biological Processlipopolysaccharide-mediated signaling pathway
Biological Processnegative regulation of B cell proliferation
Biological Processnegative regulation of ERK1 and ERK2 cascade
Biological Processnegative regulation of MAP kinase activity
Biological Processnegative regulation of mast cell proliferation
Biological Processnegative regulation of myeloid leukocyte differentiation
Biological Processnegative regulation of toll-like receptor 2 signaling pathway
Biological Processnegative regulation of toll-like receptor 4 signaling pathway
Biological Processneuroinflammatory response
Biological Processneuron projection development
Biological Processpeptidyl-tyrosine phosphorylation
Biological Processplatelet degranulation
Biological Processpositive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
Biological Processpositive regulation of cell migration
Biological Processpositive regulation of dendritic cell apoptotic process
Biological Processpositive regulation of MAPK cascade
Biological Processpositive regulation of mast cell proliferation
Biological Processpositive regulation of neuron projection development
Biological Processpositive regulation of protein phosphorylation
Biological Processprotein autophosphorylation
Biological Processregulation of B cell apoptotic process
Biological Processregulation of B cell receptor signaling pathway
Biological Processregulation of cell adhesion mediated by integrin
Biological Processregulation of cytokine production
Biological Processregulation of erythrocyte differentiation
Biological Processregulation of inflammatory response
Biological Processregulation of mast cell activation
Biological Processregulation of mast cell degranulation
Biological Processregulation of monocyte chemotaxis
Biological Processregulation of platelet aggregation
Biological Processregulation of release of sequestered calcium ion into cytosol
Biological Processresponse to hormone
Biological Processtolerance induction to self antigen
Biological Processtoll-like receptor 4 signaling pathway

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Tyrosine-protein kinase
  • EC number

Gene names

    • Name
      Lyn

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Castorimorpha > Heteromyidae > Dipodomyinae > Dipodomys

Accessions

  • Primary accession
    A0A1S3EKB5

Proteomes

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for compositional bias, region, domain.

Type
IDPosition(s)Description
Compositional bias1-16Basic and acidic residues
Region1-62Disordered
Compositional bias23-55Polar residues
Domain63-123SH3
Domain129-226SH2
Domain247-501Protein kinase

Sequence similarities

Belongs to the protein kinase superfamily. Tyr protein kinase family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    512
  • Mass (Da)
    58,723
  • Last updated
    2017-04-12 v1
  • MD5 Checksum
    D23DE86ACFF6A9EAD6745D1DC4002C7E
MGCIKSKRKDNLNDDGVDLKTQPVRNTDRTIYVRDPTSNKQQRPVSDSQLLPGQRFQTKDPEEQGDIVVALYPYDGIHPDDLSFKKGEKMKVLEEHGEWWKAKSLSTKREGFIPSNYVAKVNTLETEEWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDYDPVHGDVIKHYKIRSLDNGGYYISPRITFPCISDMIKHYQKQPDGLCRRLEKACISPKPQKPWDKDAWEIPRESIKLVKKLGAGQFGEVWMGYYNNSTKVAVKTLKPGTMSVQAFLEEANLMKSLQHDKLVRLYAVVTREEPIYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQGYRMPRMENCPDELYEIMKMCWKEKAEERPTFDYLQSVLDDFYTATEGQYQQQP

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
A0A1S3EMU2A0A1S3EMU2_DIPORLyn491

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1-16Basic and acidic residues
Compositional bias23-55Polar residues

Keywords

Sequence databases

Genome annotation databases

Similar Proteins

Disclaimer

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