A0A1S2N303 · A0A1S2N303_9MICC

  • Protein
    3-phosphoshikimate 1-carboxyvinyltransferase
  • Gene
    aroA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site263-phosphoshikimate (UniProtKB | ChEBI)
Binding site26phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site273-phosphoshikimate (UniProtKB | ChEBI)
Binding site313-phosphoshikimate (UniProtKB | ChEBI)
Binding site97phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site125phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site1723-phosphoshikimate (UniProtKB | ChEBI)
Binding site1733-phosphoshikimate (UniProtKB | ChEBI)
Binding site1743-phosphoshikimate (UniProtKB | ChEBI)
Binding site174phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site2013-phosphoshikimate (UniProtKB | ChEBI)
Active site322Proton acceptor
Binding site3223-phosphoshikimate (UniProtKB | ChEBI)
Binding site3493-phosphoshikimate (UniProtKB | ChEBI)
Binding site353phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site394phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site419phosphoenolpyruvate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Function3-phosphoshikimate 1-carboxyvinyltransferase activity
Biological Processamino acid biosynthetic process
Biological Processaromatic amino acid family biosynthetic process
Biological Processchorismate biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    3-phosphoshikimate 1-carboxyvinyltransferase
  • EC number
  • Alternative names
    • 5-enolpyruvylshikimate-3-phosphate synthase
      (EPSP synthase
      ; EPSPS
      )

Gene names

    • Name
      aroA
    • ORF names
      BK826_03370

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • LCT-H5
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Micrococcales > Micrococcaceae > Rothia

Accessions

  • Primary accession
    A0A1S2N303

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Monomer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain14-425Enolpyruvate transferase

Sequence similarities

Belongs to the EPSP synthase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    437
  • Mass (Da)
    45,681
  • Last updated
    2017-04-12 v1
  • Checksum
    E2482C7864BD0F4F
MPDPWPAPHRGTERPVHAVVAVPGSKSLTNRHLLLAAVADAPMRIRGALDSRDSRLMIEALRALGARIRTQGRDLLITPVPEEPSDEPAVIDAGLAGTVMRFIPPLAAALGRGIVLDGDAAARRRPMGPVLEAVRQLGARVHEDGEAGALPVRIEPGAGEAAPELRIDASGSSQFLSGVLLAAALLPQGLTVRHVGAELPSVPHVRMTVQVLAEYGIDVAHPDPATWVVPAGRPRAHDAVIEPDLSNAGPFLAAAVVTGGEVQIPDWPQRTTQGGDTWRELLPRFGASVHRTPDGGLRVTGPEGGAGALTAPGEIDLRAAGEIAPTVAAIAALCPGTTRLSGIAHLRGHETDRLAALAAELTRLGARTEETDDGLVITGPAHRAARMRTYEDHRIATAAAVLGLIVPGVLVEDIGTTGKTLPDFPGLWRRMLGQERA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MODZ01000003
EMBL· GenBank· DDBJ
OIJ36532.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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