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A0A1S1HT41 · A0A1S1HT41_PROST

  • Protein
    Bifunctional chorismate mutase/prephenate dehydratase
  • Gene
    pheA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Predicted
  • Annotation score
    3/5

Function

function

Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Amino-acid biosynthesis; L-phenylalanine biosynthesis; phenylpyruvate from prephenate: step 1/1.
Metabolic intermediate biosynthesis; prephenate biosynthesis; prephenate from chorismate: step 1/1.

Features

Showing features for binding site, site.

Type
IDPosition(s)Description
Binding site11substrate
Binding site28substrate
Binding site39substrate
Binding site48substrate
Binding site52substrate
Binding site84substrate
Binding site88substrate
Site278Essential for prephenate dehydratase activity

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionchorismate mutase activity
Molecular Functionprephenate dehydratase activity
Biological Processchorismate metabolic process
Biological ProcessL-phenylalanine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Bifunctional chorismate mutase/prephenate dehydratase
  • EC number
  • Alternative names
    • Chorismate mutase-prephenate dehydratase
    • p-protein

Gene names

    • Name
      pheA
    • ORF names
      A3Q29_02185
      , RG298_003933

Organism names

  • Taxonomic identifier
  • Organism
  • Strains
    • Crippen
    • 2021GO-0154
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Morganellaceae > Providencia

Accessions

  • Primary accession
    A0A1S1HT41

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-92Chorismate mutase
Domain105-285Prephenate dehydratase
Domain299-376ACT

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    390
  • Mass (Da)
    43,674
  • Last updated
    2017-04-12 v1
  • MD5 Checksum
    883DEB7D4091B894278D6E533C47A4F2
MDNSTNLLKVREKISQLDSELLGLLAKRRGYAVEVAQTKLEDNRPIRDKERERQLLDVLIDKAKPLGLDGFYVTRLFQMIIEDSVLTQQAILQQHLNLTPSDSARFAFLGPKGSYSHIAARQYSARHFDQLVECSCHKFQDIFSLVESGQADYGILPIENTSSGAINDVYDLLQNTTLSIVGEIRLPINHCLLTSCDTDLSKIDTVYSHPQPFQQCSQYLSQYPHWKIEYCDSTSTAMQKVAQQNSPNVAALGSEAGGALYNLQVLEHNLANQQINMTRFIVVAPQAIEVTEQVPAKTTLLITTGQQAGALVDALVILKNNKIIMSKLESRPINGKPWEEMFYIDVHSNLRTENMQQALKDLSAITRSIKILGCYPSENIVPVEPEKITP

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
ABMABF030000016
EMBL· GenBank· DDBJ
EMJ5136142.1
EMBL· GenBank· DDBJ
Genomic DNA
LVIE01000112
EMBL· GenBank· DDBJ
OHT24556.1
EMBL· GenBank· DDBJ
Genomic DNA

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Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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