A0A1R3S2W3 · A0A1R3S2W3_ASPC5

Function

Features

Showing features for active site, binding site.

156450100150200250300350400450500550
TypeIDPosition(s)Description
Active site219Proton acceptor
Binding site227Zn2+ (UniProtKB | ChEBI)
Binding site230Zn2+ (UniProtKB | ChEBI)
Binding site249Zn2+ (UniProtKB | ChEBI)
Binding site252Zn2+ (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmating-type region heterochromatin
Cellular Componentnucleus
Molecular Functionmetal ion binding
Molecular FunctionNAD+ binding
Molecular FunctionNAD-dependent histone deacetylase activity
Molecular Functiontransferase activity
Biological Processnegative regulation of transcription by RNA polymerase II
Biological Processpericentric heterochromatin formation
Biological Processregulation of DNA repair
Biological Processreplication-born double-strand break repair via sister chromatid exchange

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Deacetylase sirtuin-type domain-containing protein

Gene names

    • ORF names
      ASPCADRAFT_202898

Organism names

  • Taxonomic identifier
  • Strain
    • ITEM 5010
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Eurotiomycetes > Eurotiomycetidae > Eurotiales > Aspergillaceae > Aspergillus > Aspergillus subgen. Circumdati

Accessions

  • Primary accession
    A0A1R3S2W3

Proteomes

Organism-specific databases

Subcellular Location

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, compositional bias, domain.

TypeIDPosition(s)Description
Region1-73Disordered
Compositional bias18-32Pro residues
Domain75-393Deacetylase sirtuin-type
Region392-564Disordered
Compositional bias404-418Polar residues
Compositional bias435-449Polar residues
Compositional bias493-507Basic and acidic residues

Sequence similarities

Belongs to the sirtuin family. Class I subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    564
  • Mass (Da)
    61,875
  • Last updated
    2017-04-12 v1
  • Checksum
    46972918E82C3696
MDDDSDCSSLSSAPASPLAPPGFYPSPPPSQDADEPSAARSQDDLPPARKKRRVAAPKERRTQHLDLSATADHSYAQQQSQIDYLVKTLTRHRKIVVIAGAGISTSAGIPDFRSTDGLFKTLQKKHNLKASGKLLFDAAVYQDETLTASFQDMVRSLSEEAANTSPTAFHHMLARLGQENRLTRLYTQNIDGIETSMPPLATQIPLNVKAPWPRTIQLHGSLDKMVCQKCRHLSDFDRVLFDRPDAPECPECSRNNQFRIETGQRSHGIGKMRPRIVLYNEHNPDEEAITSVMNADIRSRPDALIVVGTSLKIPGVRRLVKSLCSVIRSRRNGVTMWINNEYPVGKEFEDCWDLMVKGDCEEVARLANLKRWDAKDDVFDECNSSEVERVKREQGEVSVVVTPSKKRPTPTGFLTPSSSHDEALPLPKRGCSNPASRGRSLQDVLQASKTTGPKKAAPKKGAPRGRAKKAEPAKNSKINSFGRVTKAQKAAANDKSTKLDKDDTKPMHPLAPGAARNNGPNVVANSAGKGEATPPRVGQWGRDDTISPGSIPRGMNRLLNEPTA

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias18-32Pro residues
Compositional bias404-418Polar residues
Compositional bias435-449Polar residues
Compositional bias493-507Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KV907493
EMBL· GenBank· DDBJ
OOG01038.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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