A0A1R3JFV4 · A0A1R3JFV4_COCAP
- Protein6-phosphogluconate dehydrogenase, decarboxylating
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids484 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO2, with concomitant reduction of NADP to NADPH.
Catalytic activity
- 6-phospho-D-gluconate + NADP+ = D-ribulose 5-phosphate + CO2 + NADPH
Pathway
Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 3/3.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 11-16 | NADP+ (UniProtKB | ChEBI) | |||
Binding site | 34-36 | NADP+ (UniProtKB | ChEBI) | |||
Binding site | 78-80 | NADP+ (UniProtKB | ChEBI) | |||
Binding site | 106 | NADP+ (UniProtKB | ChEBI) | |||
Binding site | 106 | substrate; ligand shared between dimeric partners; in other chain | |||
Binding site | 132-134 | substrate; ligand shared between dimeric partners; in other chain | |||
Active site | 186 | Proton acceptor | |||
Binding site | 189-190 | substrate; ligand shared between dimeric partners; in other chain | |||
Active site | 193 | Proton donor | |||
Binding site | 194 | substrate; ligand shared between dimeric partners; in other chain | |||
Binding site | 264 | substrate; ligand shared between dimeric partners; in other chain | |||
Binding site | 291 | substrate; ligand shared between dimeric partners; in other chain | |||
Binding site | 454 | substrate; ligand shared between dimeric partners | |||
Binding site | 460 | substrate; ligand shared between dimeric partners | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | NADP binding | |
Molecular Function | phosphogluconate dehydrogenase (decarboxylating) activity | |
Biological Process | D-gluconate catabolic process | |
Biological Process | pentose-phosphate shunt, oxidative branch |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name6-phosphogluconate dehydrogenase, decarboxylating
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Malvales > Malvaceae > Grewioideae > Apeibeae > Corchorus
Accessions
- Primary accessionA0A1R3JFV4
Proteomes
Genome annotation databases
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 182-476 | 6-phosphogluconate dehydrogenase C-terminal | |||
Sequence similarities
Belongs to the 6-phosphogluconate dehydrogenase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length484
- Mass (Da)53,546
- Last updated2017-04-12 v1
- MD5 ChecksumC3BB72988EFC71B9D6357AEAF44032B7
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AWWV01008062 EMBL· GenBank· DDBJ | OMO93671.1 EMBL· GenBank· DDBJ | Genomic DNA |