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A0A1R2B063 · A0A1R2B063_9CILI

  • Protein
    Phosphodiesterase
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Cofactor

a divalent metal cation (UniProtKB | Rhea| CHEBI:60240 )

Note: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

Features

Showing features for active site, binding site.

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Type
IDPosition(s)Description
Active site371Proton donor
Binding site371-375AMP (UniProtKB | ChEBI)
Binding site375Zn2+ 1 (UniProtKB | ChEBI)
Binding site411Zn2+ 1 (UniProtKB | ChEBI)
Binding site412AMP (UniProtKB | ChEBI)
Binding site412Zn2+ 1 (UniProtKB | ChEBI)
Binding site412Zn2+ 2 (UniProtKB | ChEBI)
Binding site522AMP (UniProtKB | ChEBI)
Binding site522Zn2+ 1 (UniProtKB | ChEBI)
Binding site573AMP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentmembrane
Molecular Function3',5'-cyclic-nucleotide phosphodiesterase activity
Molecular Functionmetal ion binding
Biological Processsignal transduction

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phosphodiesterase
  • EC number

Gene names

    • ORF names
      SteCoe_31946

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • WM001
  • Taxonomic lineage
    Eukaryota > Sar > Alveolata > Ciliophora > Postciliodesmatophora > Heterotrichea > Heterotrichida > Stentoridae > Stentor

Accessions

  • Primary accession
    A0A1R2B063

Proteomes

Subcellular Location

Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane16-35Helical
Transmembrane42-64Helical
Transmembrane76-100Helical
Transmembrane131-147Helical

Keywords

  • Cellular component

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain293-619PDEase

Sequence similarities

Belongs to the cyclic nucleotide phosphodiesterase family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    643
  • Mass (Da)
    73,889
  • Last updated
    2017-04-12 v1
  • MD5 Checksum
    B1E8D4A1D4F1CDC44AA87F94B763B18C
MISNKGTSLKVNNRYYIMYYCLLLYLLGHSLAFYHNYGHPKVLVVGMVLEFVLLIISLSIILANHHYESNDKVLQISFMSLYLITGLTIIFTEPSVILFLTESIKSNFLHGYFTLSIYITLGSKSIFARRIWLFICSYIVLALYSAFCFVKSNDKPEIVISAVLLGIEVYYKAGEIKCLSKNYKIVITEQEQILGYNDEAKTPLDEIIFELKQAIEKFEKLAQSSGSKMKVPSKEIKYLLEGVLKKLQANNIYSSRLDLVTKNMDIENKLYIEQEFFESHGSSVLSPPDNIQPKNVIEYSMIELLGILKPIGLEWNFNTFFVSECSRAPIKVIGEYTIKLYRLEETFKFPECKMINLLSKIESNYFDNPYHNSCHAADVLCSYIYLISNSIIKRYINSLEWLGSILACLAHDVRHPAKNNRYLIMTQNDYSITYNDISVLENMHSSTLFSFLQISDSNILSDFTIDKYQQIRKIIIDMILATDMGKHFDLISYMKNKYSEDVDFANGDTRGDLLKIFIKAADVGHAAKCIELHEKWCKLVLEEFFAQGDLEKSKGIPISMFCDRENTNINKSQAGFIKNIVLSLYETLNFIVNSEEIDVNCVKQLKLNLKYWESAQSPRLQSSTEKDEFGFGSLRNVRRGSSP

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MPUH01001119
EMBL· GenBank· DDBJ
OMJ70148.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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