A0A1R1H8N6 · A0A1R1H8N6_ACTNA

  • Protein
    Inorganic pyrophosphatase
  • Gene
    ppa
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for binding site, active site.

116620406080100120140160
TypeIDPosition(s)Description
Binding site8Mg2+ 2 (UniProtKB | ChEBI)
Binding site16substrate
Binding site30substrate
Binding site42substrate
Binding site52Mg2+ 1 (UniProtKB | ChEBI)
Binding site57Mg2+ 1 (UniProtKB | ChEBI)
Binding site57Mg2+ 2 (UniProtKB | ChEBI)
Binding site84Mg2+ 3 (UniProtKB | ChEBI)
Active site89Proton acceptor
Binding site89Mg2+ 1 (UniProtKB | ChEBI)
Binding site89Mg2+ 3 (UniProtKB | ChEBI)
Binding site126substrate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functioninorganic diphosphate phosphatase activity
Molecular Functionmagnesium ion binding
Biological Processphosphate-containing compound metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Inorganic pyrophosphatase
  • EC number
  • Alternative names
    • Pyrophosphate phospho-hydrolase
      (PPase
      )

Gene names

    • Name
      ppa
    • ORF names
      BKH33_09170

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • NCTC 10301
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Actinomycetales > Actinomycetaceae > Actinomyces

Accessions

  • Primary accession
    A0A1R1H8N6

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homohexamer.

Family & Domains

Sequence similarities

Belongs to the PPase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    166
  • Mass (Da)
    19,191
  • Last updated
    2017-04-12 v1
  • Checksum
    062222E64B973849
MEFDVTIEIPKGNRNKYEIDHETGRIRLDRMLFTSTRYPDDYGYIDGTLGEDGDPLDALVLLEEPTFPGCVIRCRALGMFRMRDEKGGDDKVLCVPSADQRASWRTDIEDVSEFHRLEIQHFFEVYKDLEPGKSVEGAHWVGREEAEEEIRQSFQREADHIARGGH

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MSRR01000018
EMBL· GenBank· DDBJ
OMG35043.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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