A0A1Q7K2X2 · A0A1Q7K2X2_9ARCH

Function

function

Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Cofactor biosynthesis; pyridoxal 5'-phosphate biosynthesis.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site59-61L-glutamine (UniProtKB | ChEBI)
Active site91Nucleophile
Binding site123L-glutamine (UniProtKB | ChEBI)
Binding site152-153L-glutamine (UniProtKB | ChEBI)
Active site188
Active site188Charge relay system
Active site190
Active site190Charge relay system

GO annotations

AspectTerm
Molecular Functionglutaminase activity
Molecular Functionpyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity
Molecular Functiontransferase activity
Biological Processglutamine catabolic process
Biological Processpyridoxal phosphate biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Pyridoxal 5'-phosphate synthase subunit PdxT
  • EC number
  • Alternative names
    • Pdx2
    • Pyridoxal 5'-phosphate synthase glutaminase subunit
      (EC:3.5.1.2
      ) . EC:3.5.1.2 (UniProtKB | ENZYME | Rhea)

Gene names

    • Name
      pdxT
    • ORF names
      AUJ08_06355

Organism names

Accessions

  • Primary accession
    A0A1Q7K2X2

Proteomes

Interaction

Subunit

In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

Family & Domains

Sequence similarities

Belongs to the glutaminase PdxT/SNO family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    214
  • Mass (Da)
    23,184
  • Last updated
    2017-04-12 v1
  • Checksum
    1E0521AAB3725F9F
MSGKKKSVIIGVLGFQGDIEENVAATKDALQDLQVEGSIELVRYPEEAEKVDGLILPGGESTVQSTLAAIQRSLPVIKKRISEGMPVLGTCAGMIMLSRRAFDRVIGDTKQKLIGNLDVVIERNAFGRQGDSFEADLDIGMLGKEVFKGVFIRAPAVSEVGKDVEVIAKLNNKIVAIKQKNIIGTSFHPELSGDSRMHRHFVKMAVDLKNKVAA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MNFY01000231
EMBL· GenBank· DDBJ
OLC82528.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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