A0A1Q7K2X2 · A0A1Q7K2X2_9ARCH
- ProteinPyridoxal 5'-phosphate synthase subunit PdxT
- GenepdxT
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids214 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
Catalytic activity
- H2O + L-glutamine = L-glutamate + NH4+
Pathway
Cofactor biosynthesis; pyridoxal 5'-phosphate biosynthesis.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 59-61 | L-glutamine (UniProtKB | ChEBI) | ||||
Sequence: GES | ||||||
Active site | 91 | Nucleophile | ||||
Sequence: C | ||||||
Binding site | 123 | L-glutamine (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Binding site | 152-153 | L-glutamine (UniProtKB | ChEBI) | ||||
Sequence: IR | ||||||
Active site | 188 | |||||
Sequence: H | ||||||
Active site | 188 | Charge relay system | ||||
Sequence: H | ||||||
Active site | 190 | |||||
Sequence: E | ||||||
Active site | 190 | Charge relay system | ||||
Sequence: E |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | glutaminase activity | |
Molecular Function | pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity | |
Molecular Function | transferase activity | |
Biological Process | glutamine catabolic process | |
Biological Process | pyridoxal phosphate biosynthetic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePyridoxal 5'-phosphate synthase subunit PdxT
- EC number
- Alternative names
Gene names
Organism names
- Taxonomic lineageArchaea > Nitrososphaerota
Accessions
- Primary accessionA0A1Q7K2X2
Proteomes
Interaction
Subunit
In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.
Structure
Sequence
- Sequence statusComplete
- Length214
- Mass (Da)23,184
- Last updated2017-04-12 v1
- Checksum1E0521AAB3725F9F