A0A1Q7JZP8 · A0A1Q7JZP8_9ARCH
- ProteinHomoserine kinase
- GenethrB
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids307 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
Catalytic activity
- ATP + L-homoserine = ADP + H+ + O-phospho-L-homoserine
Pathway
Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 4/5.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | membrane | |
Molecular Function | ATP binding | |
Molecular Function | homoserine kinase activity | |
Biological Process | threonine biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameHomoserine kinase
- EC number
- Short namesHK ; HSK
Gene names
Organism names
- Taxonomic lineageArchaea > Nitrososphaerota
Accessions
- Primary accessionA0A1Q7JZP8
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 248-269 | Helical | ||||
Sequence: AILAGALAVTISGAGPSIIAFL |
Keywords
- Cellular component
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 80-147 | GHMP kinase N-terminal | ||||
Sequence: EIHVTKGVPAGYGIGSSAASAAAAAMAFNALYNLKIDKNRLVEYAAEGEIASAGTKHYDNVSASLLGG | ||||||
Domain | 213-287 | GHMP kinase C-terminal | ||||
Sequence: FALKDIEMIATGIDDVIVEPTRKHLIPGYDGVKQNAILAGALAVTISGAGPSIIAFLKTSKNANKVAAAMAKGFE |
Sequence similarities
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length307
- Mass (Da)31,973
- Last updated2017-04-12 v1
- ChecksumD621588CF9CDE2E7