A0A1Q7EER1 · A0A1Q7EER1_9BACT
- ProteinProtein translocase subunit SecA
- GenesecA
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids924 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
Catalytic activity
Cofactor
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 87 | ATP (UniProtKB | ChEBI) | |||
Binding site | 105-109 | ATP (UniProtKB | ChEBI) | |||
Binding site | 528 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cell envelope Sec protein transport complex | |
Cellular Component | cytosol | |
Cellular Component | plasma membrane | |
Molecular Function | ATP binding | |
Molecular Function | metal ion binding | |
Biological Process | intracellular protein transmembrane transport | |
Biological Process | protein import | |
Biological Process | protein targeting | |
Biological Process | protein transport by the Sec complex |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameProtein translocase subunit SecA
- EC number
Gene names
Organism names
- Taxonomic lineageBacteria > Candidatus Rokuibacteriota
Accessions
- Primary accessionA0A1Q7EER1
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Peripheral membrane protein
Membrane ; Peripheral membrane protein
Note: Distribution is 50-50.
Keywords
- Cellular component
Interaction
Subunit
Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain, region.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 3-647 | SecA family profile | |||
Domain | 89-265 | Helicase ATP-binding | |||
Domain | 453-663 | Helicase C-terminal | |||
Region | 871-903 | Disordered | |||
Sequence similarities
Belongs to the SecA family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length924
- Mass (Da)104,183
- Last updated2017-04-12 v1
- MD5 Checksum7065A7934FC5FD19C50C3864E9F03BA8
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
MNEF01000124 EMBL· GenBank· DDBJ | OLC12008.1 EMBL· GenBank· DDBJ | Genomic DNA |