A0A1Q5RYY6 · A0A1Q5RYY6_9BRAD

Function

function

This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

  • Release of signal peptides from bacterial membrane prolipoproteins. Hydrolyzes -Xaa-Yaa-Zaa-|-(S,diacylglyceryl)Cys-, in which Xaa is hydrophobic (preferably Leu), and Yaa (Ala or Ser) and Zaa (Gly or Ala) have small, neutral side chains.
    EC:3.4.23.36 (UniProtKB | ENZYME | Rhea)

Pathway

Protein modification; lipoprotein biosynthesis (signal peptide cleavage).

Features

Showing features for active site.

116420406080100120140160
TypeIDPosition(s)Description
Active site118
Active site140

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionaspartic-type endopeptidase activity
Biological Processproteolysis

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Lipoprotein signal peptidase
  • EC number
  • Alternative names
    • Prolipoprotein signal peptidase
    • Signal peptidase II
      (SPase II
      )

Gene names

    • Name
      lspA
    • ORF names
      AC630_15165

Organism names

  • Taxonomic identifier
  • Strain
    • AS23.2
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Alphaproteobacteria > Hyphomicrobiales > Nitrobacteraceae > Bradyrhizobium

Accessions

  • Primary accession
    A0A1Q5RYY6

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane6-29Helical
Transmembrane41-59Helical
Transmembrane65-84Helical
Transmembrane91-113Helical
Transmembrane133-152Helical

Keywords

PTM/Processing

Keywords

Family & Domains

Sequence similarities

Belongs to the peptidase A8 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    164
  • Mass (Da)
    17,460
  • Last updated
    2017-04-12 v1
  • MD5 Checksum
    8AD92DA5F83F8BC5B98C0A6F88270D88
MTPLRAGILSAIVTVILDQASKLWLLNVFDLAHRGVVRVTPFFDLVLAWNIGISFGWLQNDSQEAQIALMAVKAVAVVALAIWMARSHTRLATVALGLIIGGAIGNGIDRLAYGAVVDFALFHIEIGGNTFNWYVFNLADVAIVAGVAALLYDSFLGVPAAKAP

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LGHM01000066
EMBL· GenBank· DDBJ
OKO80914.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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